Results 151 to 160 of about 6,421,048 (404)

MULTI-PHASE SIMULATION OF THE LIQUID COOLANT FLOW AROUND ROTATING CUTTING TOOL

open access: diamond, 2021
Lukáš Topinka   +3 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Phase stability and enhanced mechanical properties of nanocrystalline PVD CrCu coatings

open access: yesJournal of Materials Research and Technology
The current work investigates the possibility of strengthening grain boundaries by nanoprecipitates using a CrCu coating model system. To this end, two compositions with 30 and 40 at.% of Cu and a balanced amount of Cr were synthesized via physical vapor
Michael Burtscher   +6 more
doaj   +1 more source

Material Extrusion to Manufacture Carbide-Based Advanced Cutting Tools. [PDF]

open access: yesMaterials (Basel), 2023
Oliveira G   +4 more
europepmc   +1 more source

Using the Finite Element Method to Determine the Temperature Distributions in Hot-wire Cutting. [PDF]

open access: yes, 2011
Hot-wire cutting is a common material removal process used to shape and sculpt plastic foam materials, such as expanded polystyrene (EPS). Due to the low cost and sculpt-ability of plastic foams they are popular materials for large sized (> 1 m³ ...
Aitchison, David   +1 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Совершенствование конструкций сборных отрезных резцов для тяжелых токарных станков [PDF]

open access: yes, 2012
В данной статье рассмотрены вопросы совершенствования сборных конструкций резцов для тяжелых станков с целью повышения прочности режущей части и повышения жесткости крепления режущих элементов.
Гузенко, В. С.   +2 more
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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