Results 31 to 40 of about 4,304 (208)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Relational Analysis for Tool Vibration and Distribution Characteristics of Processing Surface Topography

open access: yesJournal of Harbin University of Science and Technology, 2019
In order to study the influence of tool vibration on the distribution characteristics of processing surface topography along spindle direction in turning largepitch thread, the experiment of turning external thread with pitch 16mm was conducted to obtain
JIANG Bin, ZHANG Fang, LI Zhe
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Grinding efficiency improvement of hydraulic cylinders parts for mining equipment

open access: yesE3S Web of Conferences, 2017
The aim of the article is to find out ways to improve parts treatment and components of mining equipment on the example of hydraulic cylinders parts, used as pillars for mine roof supports, and other actuator mechanisms.
Korotkov Aleksandr   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Influence of Cutting Parameters and Tool Edge Geometries on the Machinability of AISI 52100 Steel in Hard Whirling

open access: yesEngineering Transactions, 2023
The synergistic effect of prepared tool edge and cutting parameters in hard whirling is still unclear, limiting its application in producing large precision ball screws.
Shuquan SONG   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Characterization of monolayer and single-pass pure Cu coatings applied to 6061 T6 Al alloy and AZ31B Mg alloy substrates using high-pressure cold spray technology

open access: yesJournal of Materials Research and Technology
The study of monolayer and single-pass pure Cu coatings deposited on distinct substrates using high-pressure cold spray technique is crucial for advancing the application of Cu coatings. However research in this area remains limited.
Na Xue   +8 more
doaj   +1 more source

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