Results 121 to 130 of about 128,357 (309)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

ANALYSIS OF THE RESPONSE OF COENOPOPULATIONS OF VACCINIUM MYRTILLUS L. TO EXTERNAL IMPACTS USING SIMULATION MODELLING

open access: yesВопросы лесной науки
Ground layer vegetation plays an important role in the biological cycle in forest ecosystems. However, the quantitative responses of this component to various disturbances, as well as its recovery after damage, remain poorly studied.
P. V. Frolov   +2 more
doaj   +1 more source

Spectral Asymmetry, Zeta Functions and the Noncommutative Residue

open access: yes, 2006
In this paper we study the spectral asymmetry of (possibly nonselfadjoint) elliptic PsiDO's in terms of the difference of zeta functions coming from different cuttings. Refining previous formulas of Wodzicki in the case of odd class elliptic PsiDO's, our
Ponge, Raphael
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Controlling Soil-Borne Diseases in Ohio Nurseries [PDF]

open access: yes, 1965
PDF pages:
Bart, George J., Partyka Robert E.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Evaluation of a risk assessment system for heritage railway earthworks [PDF]

open access: yes, 2013
There are currently over 100 heritage railways in the UK carrying 6.8 million passengers on 15 million passenger journeys and contributing an estimated £579 million to the UK economy.
Crapper, Martin   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Experiment and Numerical Simulation on Shale Cutting and Breaking of Special-shaped Cutter

open access: yesShiyou jixie
In order to solve the problems of low rock-breaking efficiency and short service life of PDC bit in drilling shale gas wells, a study was made on the shale cutting and breaking mechanism of special-shaped cutter.Based on typical special-shaped cutters ...
Wen Bo   +4 more
doaj  

DNA Typing Compatibility with a One Step Saliva Screening Test [PDF]

open access: yes, 2014
Screening a substrate for bodily fluids is an extremely important step for locating areas that may contain DNA. Several different methods have been developed for saliva (1).
Barloewen, Brooke   +3 more
core   +1 more source

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