Results 71 to 80 of about 18,850 (237)

Central venous catheter-associated thrombosis in children with congenital hyperinsulinism

Endocrinology, Diabetes & Metabolism Case Reports, 2019
Congenital hyperinsulinism (CHI) is an important cause of severe hypoglycaemia in infancy. To correct hypoglycaemia, high concentrations of dextrose are often required through a central venous catheter (CVC) with consequent risk of thrombosis.
Daphne Yau, Maria Salomon-Estebanez, Amish Chinoy, John Grainger, Ross J Craigie, Raja Padidela, Mars Skae, Mark J Dunne, Philip G Murray, Indraneel Banerjee   +9 more
doaj   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

Equine Veterinary Education, EarlyView.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh, C. R. Daniel, J. A. Keen, N. J. Parkinson, B. C. McGorum   +4 more
wiley   +1 more source

A clinical evaluation of two central venous catheter stabilization systems

Annals of Intensive Care, 2019
Background Central venous catheters (CVCs) are commonly secured with sutures which are associated with microbial colonization and infection. We report a comparison of a suture-free system with standard sutures for securing short-term CVC in an ...
Tarja J. Karpanen, Anna L. Casey, Tony Whitehouse, Jean-Francois Timsit, Olivier Mimoz, Mercedes Palomar, Tom S. J. Elliott   +6 more
doaj   +1 more source

RNF13 is a previously undescribed interactor of iduronate 2‐sulfatase that modifies its glycosylation and maturation

The FEBS Journal, EarlyView.
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

AUTOMATIC RECALIBRATION OF QUANTUM DEVICES BY REINFORCING LEARNING

Anales (Asociación Física Argentina)
During their operation, due to shifts in environmental conditions, devices undergo various forms of detuning from their optimal settings. Typically, this is addressed through control loops, which monitor variables and the device performance, to maintain ...
T. Crosta, L. Rebón, F. Vilariño, J.M. Matera, M. Bilkis   +4 more
doaj   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

The FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez, Noora Virtanen, Elmeri Kiviluoto, Rob C. H. Driessen, Feihu Zhao, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren   +7 more
wiley   +1 more source

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

The FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal, Valérie C. Cabana, Antoine Y. Bouchard, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

Central Venous Catheter (CVC) related infections: a local retrospective study

Microbiologia Medica, 2008
Background. Central venous catheter (CVC) related infection is associated with significant increases in morbidity, mortality, and health care cost.This local surveillance study was carry out to monitor the frequency of occurrence of CVC-related blood ...
Manuela Fresu, Agostina Ronca, Carla Pruzzo, Simona Roveta   +3 more
doaj   +1 more source

Back‐up arteriovenous fistula in peritoneal dialysis patients: a retrospective cohort study of long‐term meaningful outcomes

Internal Medicine Journal, EarlyView.
ABSTRACT Background Back‐up arteriovenous fistula (bAVF) is used in peritoneal dialysis (PD) to avoid haemodialysis transfer via a central venous catheter (CVC). However, no previous study examined mortality or complications associated with bAVF creation.
Hicham I. Cheikh Hassan, Karumathil M. Murali, Jenny H. C. Chen, Judy Mullan   +3 more
wiley   +1 more source

Correlation between visceral fat area and cardiac valve calcification in hemodialysis patients

Frontiers in Cardiovascular Medicine
ObjectiveTo investigate the relationship between Visceral Fat Area (VFA) and cardiac valve calcification (CVC) in Maintenance Hemodialysis (MHD) patients.MethodsThis cross-sectional study included MHD patients enrolled at our hospital between July 2023 ...
Xiaoqi Wang, Dan Yuan, Feng Shao, Jingjing Zhou, Xiao Zhang, Zhongxin Li   +5 more
doaj   +1 more source