Results 171 to 180 of about 80,113 (268)

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Micro-electric field-associated restructuring of bacterial communities enhances wastewater purification in constructed wetlands. [PDF]

iScience
Wang Q, Liu Y, Zhu J, Zhou H, Liu X, Yang S.   +5 more
europepmc   +1 more source

TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice

Advanced Science, EarlyView.
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo, Chuanyin Wu, Miao Feng, Wenfan Luo, Rong Miao, Jinsheng Qian, Fan Wang, Chunlei Zhou, Bojuan Liu, Jiale Shao, Ziqi Xun, Yehui Xiong, Zhichao Zhao, Cailin Lei, Shanshan Zhu, Yulong Ren, Xin Wang, Xiuping Guo, Haiyang Wang, Zichao Li, Zhijun Cheng, Qibing Lin, Jianmin Wan   +22 more
wiley   +1 more source

Terpenoid-enriched <i>Curcuma wenyujin</i> nanovesicles for suppressing inflammation and restoring lipid homeostasis in MASH. [PDF]

Extracell Vesicles Circ Nucl Acids
Liu L, Niu J, Sun Y, He Z, Jiao Z, Li G, Wang G, Luo F, Li W.   +8 more
europepmc   +1 more source

Battery‐Inspired Electrochemical Synapses for Neuromorphic Applications

Advanced Science, EarlyView.
Battery‐ion‐inspired synaptic devices integrate diverse electrolyte systems (solid, ion‐gel, liquid) with transition metal oxides, two‐dimensional materials, and organic channels to regulate ion‐electron coupling. By tailoring ion transport and host interactions, these platforms enable controllable plasticity and energy‐efficient implementations for ...
Won Woo Lee, SeongCheol Jang, Wangmyung Choi, Jaewon Park, Jaehyun Hur, Hocheon Yoo, Hyun‐Suk Kim   +6 more
wiley   +1 more source

Detection of Degraded Formulated BaTiO3 Induced by Oxygen Vacancy Migration Using Ultrasonic Attenuation

Advanced Science, EarlyView.
Oxygen vacancy migration is a key degradation mechanism for the majority of MLCCs. There are limitations with spatially identifying regions of a capacitor that have degraded due to oxygen vacancy migration. This work showcases ultrasonic attenuation as a non‐electrical and nondestructive technique of identifying oxygen vacancy degraded regions of an ...
Haley N. Jones, Clive A. Randall, Andrea P. Argüelles, Susan Trolier‐McKinstry   +3 more
wiley   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Winter activity and virus infection of Culicoides biting midges (Diptera: Ceratopogonidae) in German livestock housing before and during the 2024 BTV-3 outbreak. [PDF]

Parasit Vectors
Voigt A, Kampen H, Beer M, Wernike K, Scheuch D, Sick F, Zeiske S, Werner D.   +7 more
europepmc   +1 more source

Architecting Phase‐Selective Interlayers for Stable SiOx Lithium Storage via Dual‐Function Design

Advanced Science, EarlyView.
Silicon anodes offer high capacity but suffer severe volume expansion. Silicon monoxide (SiO) buffers expansion, yet uncontrolled lithiation irreversibly consumes lithium as Li2O and oxygen‐rich silicates. Here, we design a layered SiOx featuring a phase‐selective conductive interfacial interlayer (PSCII), i.e., a Li4SiO4‐rich, ion‐accessible ...
Zhenfei Chang, Wei Dong, Yingguang Zhang, Hangchen Qu, Yifei Wang, Xiaolong Zhao, Chu Wang, Ming Dong, Huizhi Wang, Jin Xuan, Yug Joshi, Dennis Y.C. Leung, Wending Pan   +12 more
wiley   +1 more source

EPR spectroscopy 80 years after its discovery. [PDF]

Sci Adv
Goldfarb D, Jeschke G, McInnes EJL, Prisner T, Schiemann O, Stoll S.   +5 more
europepmc   +1 more source