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Is cyanate a carbonic anhydrase substracte?
Proteins: Structure, Function, and Genetics, 1997A study was undertaken to investigate whether diverse carbonic anhydrase (CA) isozymes (both native Zn as well as cobalt-substituted) are able to catalyze the hydrolysis of anions such as cyanide, cyanate, and thiocyanate. A controversy exists between the crystallographic and spectroscopic data of CA II-anion adducts.
SUPURAN, CLAUDIU TRANDAFIR +2 more
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Anodic cyanation of tetramethylthiophene
Journal of the Chemical Society, Perkin Transactions 1, 1991AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
K. Minagawa, K. Yoshida, Kazuyuki Takeda
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Nuclear cyanation of diphenylacetylene
Journal of the Chemical Society D: Chemical Communications, 1970Electrochemical oxidation of diphenylacetylene in methanol in the presence of sodium cyanide yields p-cyanodiphenylacetylene.
Takayuki Fueno, Kunihisa Yoshida
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Reversible inactivation of papain by cyanate
Biochimica et Biophysica Acta (BBA) - Enzymology, 1967Low concentrations of KCNO (approx o.1. mM) were found to react rapidly with activated papain (EC 3.4.4.10), leading to inactivation of the enzyme. The reaction proved to be reversible, the activity slowly returning again on sufficient dilution of the enzyme-KCNO mixture.
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Cyanation of a ruthenicinium salt
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1967In the presence of ferric chloride, ruthenocene undergoes direct cyanation with the formation of the previously undescribed ruthenocenecarbonitrile. Ruthenocene is far less active in this reaction than ferrocene.
L. P. Yur'eva +4 more
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Cyanate and sickle cell anemia
Trends in Biochemical Sciences, 1976Abstract The treatment of sickle-cell patients with cyanate represents the first attempt to overcome the effects of a deleterious mutation by direct chemical modification of the mutant gene product. Human trials have revealed that oral administration of cyanate is unsafe; complications arise that were not uncovered in animal studies.
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