Antidotes for cyanide poisoning
Abstract : We read with interest the review and guideline by Anseeuw et al. [1] titled Cyanide poisoning by fire smoke inhalation: an European expert consensus . The authors reviewed the current literature succinctly and identified gaps in knowledge. They also elegantly reviewed the diagnosis of cyanide poisoning, which can be difficult. We concur with
N. Delvau+7 more
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The treatment of cyanide poisoning [PDF]
Cyanide has gained historical notoriety as a poison used with intent to cause fatality. Its occurrence in industry is confined to a small number of uses in a relatively narrow range of industries, including the manufacture of Perspex and nylon and in electroplating.
Tomas Cummings
openaire +4 more sources
Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. [PDF]
Cyanide is a potent toxic agent, and the few available antidotes are not amenable to rapid deployment in mass exposures. As a result, there are ongoing efforts to exploit different animal models to identify novel countermeasures.
Patrick Y Sips+18 more
doaj +2 more sources
In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning [PDF]
The objective of this study was to compare the use of hydroxocobalamin (B12a) and a succinate prodrug to evaluate for improvement in mitochondrial function in an in vitro model of cyanide poisoning.
Shawn Owiredu+9 more
doaj +2 more sources
Neurological Sequelae of Acute Hydrogen Sulfide Poisoning: A Literature Review, Controversies, and Knowledge Gaps [PDF]
Hydrogen sulfide (H2S) is a highly potent toxic gas, and the brain is a primary target organ following acute intoxications. Accidents and misuse of this gas for nefarious purposes, i.e., bioterrorism, are causes for concern regarding acute poisoning. The
Wilson K. Rumbeiha, Dong-Suk Kim
doaj +2 more sources
Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event [PDF]
Cyanide is rapidly reacting and causes arrest of aerobic metabolism. The symptoms are diffuse and lethal and require high clinical suspicion. Remediation of symptoms and mortality is highly dependent on quick treatment with a cyanide antidote. Presently,
Andrew Meillier, Cara Heller
doaj +2 more sources
Electrochemical aptasensor for 2-amino-2-thiazoline-4-carboxylic acid (ATCA), a metabolite for cyanide poisoning [PDF]
An alternative biomarker for assessing the cyanide levels in postmortem materials is crucial for investigating acute cyanide intoxication. Herein, an aptamer–ligand biorecognition system with high specificity was developed to detect acute cyanide ...
Hairunnisa Mohd Anas Khan+5 more
doaj +2 more sources
Accidental cyanide poisoning [PDF]
J. W. Brooks, T. A. Thomas
openaire +4 more sources
A Case of Poisoning by the Cyanide of Potassium [PDF]
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A B Arnold
openaire +4 more sources
Overview of Cyanide Poisoning in Cattle from Sorghum halepense and S. bicolor Cultivars in Northwest Italy. [PDF]
Giantin S+8 more
europepmc +3 more sources