Results 31 to 40 of about 58,586 (263)

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

open access: yesAdvanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun   +14 more
wiley   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

open access: yesAdvanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du   +9 more
wiley   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

open access: yesAdvanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su   +4 more
wiley   +1 more source

CLASSICAL CYBERNETICS CRISIS LESSONS. CAUSES AND ESSENCE

open access: yesРадіоелектронні і комп'ютерні системи, 2018
It is performed an analysis of the causes and consequences of the crisis of classical cybernetics, created by N. Wiener and W. R. Anby. N. Viener has shown that the basis of the crisis is the exclusion from the consideration of the process of forming the
Серій Ілліч Доценко
doaj   +1 more source

Talk to Your Data: An Agentic Artificial Intelligence‐Driven Decision‐Support Framework for Prosumer Energy Optimization and Recommendations

open access: yesAdvanced Intelligent Systems, EarlyView.
An agentic AI‐driven decision‐support framework for prosumers is proposed, integrating PV generation, load profiling, and multihorizon optimization within a four‐agent architecture. The approach significantly reduces grid dependence, enhances self‐sufficiency and prevents system oversizing.
Adela BÂRA, Simona‐Vasilica OPREA
wiley   +1 more source

New Cybernetics and the Application of its Principles in Physics [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2013
We describe principles of new cybernetics and use these principles for resolution of basic physical paradoxes. It demonstrates universality of the principles of new cybernetics.
Oleg Kupervasser
doaj  

Interplay Between Cybernetics and Philosophy as an Essential Condition for Learning [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2021
In the 21st century, there is an increasing interest in studying the relationship of cybernetics and philosophy. My paper is also inspired by the recent enormous efforts in developing machine intelligence and machine learning to replicate human ...
Maria Jakubik
doaj  

Adaptive Collision Sensitivity for Efficient and Safe Human–Robot Collaboration

open access: yesAdvanced Intelligent Systems, EarlyView.
An adaptive collision‐sensitivity framework uses each robot link's effective mass to estimate contact forces online and decide when collaborative robots should stop or continue. Tested on simulated and real UR10e and simulated KUKA arms, it maintains conservative force estimates while reducing unnecessary stops and increasing task productivity. What is
Lukas Rustler   +2 more
wiley   +1 more source

Morphophysiological dynamics of the proximal post‐testicular ducts in Crotalus durissus Linnaeus, 1758 (Squamata: Viperidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract The organization and function of reptilian excurrent ducts remain poorly characterized, particularly in Neotropical snakes. We provide the first integrative morphological, histochemical, immunohistochemical, and ultrastructural analysis of the proximal post‐testicular ducts of Crotalus durissus across reproductive stages.
Flávia Cappuccio de Resende   +9 more
wiley   +1 more source

All’ombra di nuove scienze in fiore. Lo strano caso della cibernetica con uno sguardo all’Italia degli anni Sessanta

open access: yesPhilosophy Kitchen, 2023
The present paper describes and discusses certain aspects of the evolution of cybernetics, with a focus on the Italian context. It considers the ways in which cybernetic questions relate to present issues of crucial importance.
Settimo Termini
doaj   +1 more source

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