Results 41 to 50 of about 180,917 (343)
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Image preprocessing models typically serve as the initial step in advanced visual tasks, aiming to enhance the performance of subsequent tasks. For example, multi-focus image fusion technology significantly improves the performance of downstream semantic
Pengcheng Zhu +6 more
doaj +1 more source
The Problem of the Political in Cyberspace
The central discussion in this paper concerns the articulation of ways whereby liminality is inscribed in cyberspace architecture, in order to show that cyberspace is a political performative space.
Aneta Stojnić
doaj +1 more source
Educating for Evolving Operational Domains: Cyber and Information Education in the Department of Defense and the Role of the College of Information and Cyberspace [PDF]
Quentin E. Hodgson +3 more
openalex +1 more source
Technology Policy, Gender, and Cyberspace [PDF]
Event based sampling occurs when the time instants are measured everytime the amplitude passes certain pre-defined levels. This is in contrast with classical signal processing where the amplitude is measured at regular time intervals.
Gustafsson, Fredrik, Persson, Niclas
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
City networks in cyberspace and time : using Google hyperlinks to measure global economic and environmental crises [PDF]
Geographers and social scientists have long been interested in ranking and classifying the cities of the world. The cutting edge of this research is characterized by a recognition of the crucial importance of information and, specifically, ICTs to cities’
Boulton, Andrew +4 more
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Editor’s Introduction: Deconstructing the Master Signifier of Community [PDF]
Deconstructing the master signifier of community: Between the pre-modern and modern community of organic solidarity and the postmodern community of technological dissemination in ...
Jagodzinski, Jan
core +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

