Results 161 to 170 of about 8,652,661 (302)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Characterization of the combustion process and cycle-to-cycle variations in a spark ignition engine fuelled with natural gas/hydrogen mixtures

, 2015
M. Reyes, Francisco V. Tinaut Fluixá, Andrés Melgar, Alvaro Ortiz Pérez   +3 more
openalex   +2 more sources

TRIM8 modulates p53 activity to dictate cell cycle arrest [PDF]

, 2012
Mariano Francesco Caratozzolo, Lucia Micale, Maria Giuseppina Turturo, S Cornacchia, Carmela Fusco, Flaviana Marzano, Bartolomeo Augello, Anna Maria D’Erchia, Luisa Guerrini, Graziano Pesole, Elisabetta Sbisà, Giuseppe Merla, Apollonia Tullo   +12 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Domestication drives repeated evolution of sexual-asexual life cycle trade-offs in yeast. [PDF]

Proc Natl Acad Sci U S A
Becerra-Rodríguez C, Thiele P, Brach G, Dutta A, Garin M, Tan G, Loegler V, Friedrich A, Andrews B, Boone C, Schacherer J, Hou J.   +11 more
europepmc   +1 more source

Moduli of surfaces with an anti-canonical cycle [PDF]

, 2014
Mark Gross, Paul Hacking, Seán Keel
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Real-world use of botulinum toxin-A for post-stroke spasticity in the Netherlands: a retrospective claims study. [PDF]

J Rehabil Med
Van Wijk M, Verhoeven M, Lysen TS, Van Ballegooijen H, Geurts ACH.   +4 more
europepmc   +1 more source

Breaking the Cycle of Gridlock

, 2018
Thomas Hale, David Held
openalex   +2 more sources