Results 51 to 60 of about 20,862,288 (311)

Signal timing estimation using point detectors

Journal of Highway and Transportation Research and Development
Compared with the traffic flows on freeways, the traffic in urban networks is significantly influenced by signal controls. Therefore, signal timing parameters are required in lots of urban research topics, including signal performance measurements and ...
Xiaoqin Luo
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Quasi-Experimental Field Assessment of Haul-Road Maintenance Effects on Fuel Consumption, Cycle Time and Mechanical Loading of Open-Pit Dump Trucks

Applied Sciences
Haul-road condition in open-pit mining affects fuel consumption, transport-cycle throughput and dump-truck mechanical loading. This study conducted a quasi-experimental field assessment of local maintenance effects on severely degraded road segments. The
Aman Tulegenovich Shakenov, Assem Yerzhankyzy Utegenova, Ivan Nikitovich Stolpovskikh, Ainura Berikbolovna Orumbassarova, Boris V. Malozyomov, Nikita V. Martyushev   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Revolutionizing JIRA Management with Artificial Intelligence: Streamlining Workflow Efficiency and Enhancing Project Outcomes

The Pinnacle
IT organizations are investing heavily on artificial intelligence (AI), though the value realization and areas of application of AI are still limited and not explored completely.
Rakhi Jain, Jeffrey Butler
doaj   +1 more source

Effect of the Martensitic Transformation on the Stamping Force and Cycle Time of Hot Stamping Parts

Metals, 2018
Stamping dies perform two functions in the hot stamping process of body-in-white components. Firstly, they form the steel sheet into the desired shape and, secondly, they quench the steel at a cooling rate that leads to hardening by means of the ...
Maider Muro, Garikoitz Artola, Anton Gorriño, Carlos Angulo   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Time consumption and productivity of a forwarder operating on a slope in a cut-to-length harvest system in a Pinus radiata D. Don pine plantation

Journal of Forest Science, 2017
Time consumption and productivity of a Valmet 890.3 8 wheel forwarder were evaluated on an Australian radiata pine clearfell site with a slope of 21 to 45% (12 to 24°). Cycle time was significantly related to extraction distance.
Martin STRANDGARD, Rick MITCHELL, Mauricio ACUNA   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Finding cycles and trees in sublinear time [PDF]

Random Structures & Algorithms, 2012
ABSTRACTWe present sublinear‐time (randomized) algorithms for finding simple cycles of length at least and tree‐minors in bounded‐degree graphs. The complexity of these algorithms is related to the distance of the graph from being Ck‐minor free (resp., free from having the corresponding tree‐minor). In particular, if the graph is ‐far from being cycle‐
Artur Czumaj, Oded Goldreich 0001, Dana Ron, C. Seshadhri 0001, Asaf Shapira, Christian Sohler   +5 more
openaire   +3 more sources