Results 81 to 90 of about 20,862,288 (311)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Time to Cycle

open access: yes
Consider the random process that starts with $n$ vertices and no edges, where the edges of $K_n$ are added one at a time in a uniformly chosen random order $e_1, e_2,\ldots, e_{\binom{n}{2}}$. Let $T$ be the earliest time at which $e_1$ belongs to a cycle in this evolving random graph. By solving the appropriate graph enumeration problem we show that $\
Lavee, Nir, Linial, Nati
openaire   +2 more sources

Measuring Business Cycle Time [PDF]

open access: yesJournal of Political Economy, 1987
The business cycle analysis of Arthur F. Burns and Wesley C. Mitchell and the National Bureau of Economic Research presumed that aggregate economic variables evolve on a time scale defined by business cycle turning points rather than by months or quarters.
openaire   +4 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The Time-to-Build Tradition in Business Cycle Modelling [PDF]

open access: yes
An important frontier of business cycle theorising is the 'time-to-build' tradition that lies at the heart of Real Business Cycle theory. Kydland and Prescott (1982) did not acknowledge the rich tradition of 'time-to-build' business cycle theorising ...
N. Dharmaraj, K. Vela Velupillai
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

TIME DELAYS AND THE UNDERWRITING CYCLE [PDF]

open access: yes
We shall consider the concept of time delays and the extent to which this is a common feature in many general insurance systems. We shall then present an example of a model of an insurance system with delays that helps to explain the phenomenon of ...
Carmen Pricină, Ovidiu Solomon
core   +2 more sources

PROCESS SIMULATOR FOR MANUAL HANDLING PESTICIDE PACKAGING ASSEMBLY LINE

open access: yesMalaysian Journal of Computing
Reducing production costs without sacrificing product quality is essential for the global market survival. The problem of line balancing, especially assembly line balancing, plays an important role for industry in achieving the highest quality and lowest
Siti Norhazlinda Roslan   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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