IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
Atherogenic lipid ratios and insulin resistance primarily reflect adiposity rather than androgen status in adolescents with polycystic ovary syndrome: evidence from a large case-control cohort. [PDF]
Jakubowska-Kowal KM +4 more
europepmc +1 more source
A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu +12 more
wiley +1 more source
An Anaplastic Pleomorphic Variant of Mantle Cell Lymphoma. [PDF]
Chiriac R, Donzel M.
europepmc +1 more source
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis +32 more
wiley +1 more source
Tislelizumab-induced Vogt-Koyanagi-Harada-like uveitis: a case report. [PDF]
Zhou Y, Lei X, Ma W.
europepmc +1 more source
Correlation Between Meso-Defect and Fatigue Life Through Representing Feature Analysis for 6061-T6 Aluminum Alloys. [PDF]
Zhang L, Yang Y, Chen H, Lv S.
europepmc +1 more source
Does Sleep Quality Affect IVF Outcomes? [PDF]
Pamfilio LS +4 more
europepmc +1 more source
Sleep variability and risk of type 2 diabetes mellitus: Mediating role of social participation in a national longitudinal cohort study. [PDF]
Zhu Y, Gong Y.
europepmc +1 more source
Impact of contact lens correction on wavefront aberrations and vision quality in keratoconus. [PDF]
Swartz G, Alam K, Gentle A, Downie LE.
europepmc +1 more source

