Results 111 to 120 of about 795,041 (278)
On Algebraic and Definable Closures for Theories of Abelian Groups
Известия Иркутского государственного университета: Серия "Математика"Classifying abelian groups and their elementary theories, a series of characteristics arises that describe certain features of the objects under consideration.
In.I. Pavlyuk
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Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
One-step synthesis of epoxy/cyclic carbonate bifunctional polycarbonates with functional groups
Carbon Capture Science & TechnologyThe synthesis of functionalized polycarbonates from CO2 has gained significant attention due to their versatile properties and potential in high-performance applications.
Jie Huang, Boxiong Shen
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Bioinorganic Chemistry and Applications, 2017 The aim of this study was to investigate the effect of 50% hydrofluoric acid (HF) surface treatment on the cyclic fatigue resistance (CFR) of K3 NiTi instruments. Twenty as-received and twenty HF-treated K3 NiTi instruments were compared in CFR.
Kee-Yeon Kum, Seok Woo Chang
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Virtually Free-by-Cyclic Groups
Geometric and Functional AnalysisAbstractWe obtain a homological characterisation of virtually free-by-cyclic groups among groups that are hyperbolic and virtually compact special. As a consequence, we show that many groups known to be coherent actually possess the stronger property of being virtually free-by-cyclic.
Kielak, D, Linton, M
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source