Results 281 to 290 of about 84,969 (338)
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Cyclic Guanosine Monophosphate in Primary Cultures of Glial Cells
Journal of Neurochemistry, 1980Abstract: Cyclic GMP was found in primary cultures of glial cells obtained by dissociation of newborn mouse brain hemispheres. Its basal level (0.52 pmoles/mg cell protein) was as high as that found in adult mouse brain cortex but 10 times lower than in cerebellum.
C. Fages, M. Bloch-Tardy, P. Gonnard
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Molecular Conformation of Guanosine 3,′5′-Cyclic Monophosphate
Nature New Biology, 1973THE molecular structure of 5′-methylene adenosine 3′,5′-cyclic monophosphonate (cyclic AMP analogue), a synthetic cyclic nucleotide, has been reported1,2. Here we report the molecular structure of the naturally occurring cyclic nucleotide guanosine 3′,5′-cyclic monophosphate (cyclic GMP).
Alice Ku Chwang, M. Sundaralingam
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Nitric oxide and cyclic guanosine monophosphate signaling in the eye
Canadian Journal of Ophthalmology, 2008This brief review describes the components and pathways utilized in nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) signaling. Since the discovery of the effects of NO and cGMP on smooth muscle relaxation about 30 years ago, the field has expanded in many directions such that many, but not all, biochemical and biological effects seem to be ...
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The Endothelium and Cyclic Guanosine Monophosphate in Hyperthyroid-Induced Hypertension
1987We investigated the role of endothelium derived relaxing factor (EDRF) and cyclic guanosine monophosphate (cGMP) in the altered vascular reactivity of hyperthyroidism (HT). Rats were given daily injections of triiodothyronine (T3), 50 micrograms/100 g body weight for two weeks, and they had significantly higher serum levels of T3 compared to untreated,
Lockette W, Otsuka Y, Hirt E
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Journal of biological regulators and homeostatic agents, 2016
The aim of this study was to evaluate whether or not the expression of cGMP- phosphodiesterases (cGMP-PDE) varies in different thyroid pathologies and to elucidate the relationship between the expression of cGMP-PDE, cGMP, and autophagy. Fifty-four thyroid biopsy samples, excised to perform the biopsy, were split into two parts and randomly assigned ...
SPOTO, Giuseppe +7 more
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The aim of this study was to evaluate whether or not the expression of cGMP- phosphodiesterases (cGMP-PDE) varies in different thyroid pathologies and to elucidate the relationship between the expression of cGMP-PDE, cGMP, and autophagy. Fifty-four thyroid biopsy samples, excised to perform the biopsy, were split into two parts and randomly assigned ...
SPOTO, Giuseppe +7 more
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Cyclic Guanosine Monophosphate Role in Human Carcinoma Pathogenesis
Nucleosides, Nucleotides and Nucleic Acids, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Di Nicola Maurizio +6 more
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Journal of Sexual Medicine, 2010
INTRODUCTION Ginsenoside Rg1 is the purified ingredient from ginseng, there has been little research on the effect of Rg1 on male copulatory behavior and its mechanism of action.
Xiaoying Wang +4 more
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INTRODUCTION Ginsenoside Rg1 is the purified ingredient from ginseng, there has been little research on the effect of Rg1 on male copulatory behavior and its mechanism of action.
Xiaoying Wang +4 more
semanticscholar +1 more source
Canadian Journal of Physiology and Pharmacology, 1982
Tetanic stimulation at different temperatures (5 and 20 °C) of the frog sartorius muscle results in an increase of cyclic guanosine monophosphate (cGMP) directly correlated to the tension developed. Cyclic adenosine monophosphate (cAMP) levels change differently for different temperature values.
Fanò G. +5 more
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Tetanic stimulation at different temperatures (5 and 20 °C) of the frog sartorius muscle results in an increase of cyclic guanosine monophosphate (cGMP) directly correlated to the tension developed. Cyclic adenosine monophosphate (cAMP) levels change differently for different temperature values.
Fanò G. +5 more
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Cyclic guanosine monophosphate phosphodiesterase activity in human gingival carcinoma
Journal of Oral Pathology & Medicine, 2003AbstractBackground: Cyclic guanosine monophosphate (cGMP) is an essential second messenger metabolized by phosphodiesterases (PDEs).Objectives: We looked for a possible correlation of PDE activities in human oral squamous cell carcinoma (OSCC) with and without lymph node metastases.Materials and methods: The analysis of phosphodiesterase activity and ...
SPOTO, Giuseppe +6 more
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Biochemical Pharmacology, 1987
The discovery and structure-activity of a new class of renal artery phosphodiesterase inhibitors is reported, some of which are highly selective for the guanosine cyclic 3',5'-monophosphate phosphodiesterase. One of these compounds, 5,6-dihydro-8,9,11,12-tetramethoxy-1,3-dioxo-1H-benz[f]- isoquino [8,1,2- hij]quinazoline-2(3H)-carboxylic acid, ethyl ...
Susan P. Buckham +4 more
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The discovery and structure-activity of a new class of renal artery phosphodiesterase inhibitors is reported, some of which are highly selective for the guanosine cyclic 3',5'-monophosphate phosphodiesterase. One of these compounds, 5,6-dihydro-8,9,11,12-tetramethoxy-1,3-dioxo-1H-benz[f]- isoquino [8,1,2- hij]quinazoline-2(3H)-carboxylic acid, ethyl ...
Susan P. Buckham +4 more
openaire +3 more sources