Results 191 to 200 of about 70,301 (265)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Nonlinear viscoelastic models improve characterisation of 6 DOF intervertebral disc load response at low strain rates. [PDF]

Proc Inst Mech Eng H
Hayward S, Keogh PS, Miles AW, Gheduzzi S.   +3 more
europepmc   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Study on the Mechanical Property Degradation Laws of 6061-T6 Aluminum Alloy Under the Synergistic Effect of Corrosion and Cyclic Loading. [PDF]

Materials (Basel)
Long Q, Nie X, Yan C, Chen Z, Li Z, Chen S, Huang Z.   +6 more
europepmc   +1 more source

Coupled effect of unloading rate and water content on mortar under differential cyclic loading. [PDF]

Sci Rep
Liu Z, Cao P, Liu L, Wang F, Han D, Xu C.   +5 more
europepmc   +1 more source

Construct strength of a drilling trajectory angled proximally avoiding the posterior interosseous nerve in single incision distal biceps repair; a comparative cadaveric study. [PDF]

JSES Rev Rep Tech
Macken AA, Shirinskiy I, van der Gaast N, van der Poel WJ, Bleys RLAW, van Deurzen DFP, Caekebeke P, Eygendaal D, van den Bekerom MPJ.   +8 more
europepmc   +1 more source

Biomechanical comparison of Mitchell versus Chevron osteotomy with the third generation minimally invasive screw fixation technique. [PDF]

BMC Musculoskelet Disord
Kuan FC, Lin CH, Huang CM, Su WR, Chiang CH, Lo SP.   +5 more
europepmc   +1 more source

Effect of Demineralization on Fatigue-Based Shear Bond Strength Across Different Orthodontic Brackets: An In Vitro Study. [PDF]

J Clin Med
Aydoğan T, Cicek O, Yetmez M.
europepmc   +1 more source

Dynamic characteristics of frozen ballast beds in cold-region railways under cyclic train loading. [PDF]

Sci Rep
Liu J, Cao Y, Chen A, Qi W, Kou L, Sysyn M.   +5 more
europepmc   +1 more source