Results 121 to 130 of about 86,821 (289)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Cyclic furnace oxidation of clad WI-52 systems at 1040 C and 1090 C [PDF]

open access: yes
Cyclic furnace oxidation studies were conducted on the cobalt alloy WI-52 clad with Ni-30Cr, Fe-25Cr-4A1, and Ni-20Cr-4A1 foils (0.051 to 0.254 mm thick).
Gedwill, M. A.
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Cyclic oxidation resistance of clad IN-100 at 1040 C and 1090 C - Time, cycle frequency, and clad thickness effects [PDF]

open access: yes
Thermal cycling tests of Cr, Al, Si, Fe, and Y alloy clad nickel alloy at 1040 and 1090 C and time, cycle frequency, and film thickness effects on oxidation ...
Gedwill, M. A.
core   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai   +2 more
wiley   +1 more source

The Impact of High‐Productivity Processing on the Fatigue Failure of an Additive Manufactured Superalloy HAYNES 282

open access: yesAdvanced Engineering Materials, EarlyView.
The low cycle fatigue life of additive manufactured HAYNES® 282® superalloy was investigated for conventional and high‐productivity processing: samples of the former lasted 1400–1700 cycles, while samples of the latter failed at ~ 1200 cycles, at 760 °C and 1% strain.
Abdul Shaafi Shaikh   +3 more
wiley   +1 more source

High temperature surface protection [PDF]

open access: yes
Alloys of the MCrAlX type are the basis for high temperature surface protection systems in gas turbines. M can be one or more of Ni, Co, or Fe and X denotes a reactive metal added to enhance oxide scale adherence.
Levine, S. R.
core   +1 more source

Laser Powder Bed Fusion of Copper–Tungsten Composites for Heat Sink Applications in High‐Power Electronics

open access: yesAdvanced Engineering Materials, EarlyView.
This article demonstrates the successful qualification of a copper–tungsten composite for laser powder bed fusion. The resulting components exhibited high density, high thermal conductivity, and reduced thermal expansion. Heat sinks with complex geometries were successfully manufactured, clearly showcasing the material's potential for additive ...
Simon Rauh   +6 more
wiley   +1 more source

Volatilization of oxides during oxidation of some superalloys at 1200 C [PDF]

open access: yes
Volatilization of oxides during cyclic oxidation of commercial Nichrome, Inconel 750, Rene 41, Stellite 6B, and GE-1541 was studied at 1200 C in static air.
Zaplatynsky, I.
core   +1 more source

Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution

open access: yesAdvanced Engineering Materials, EarlyView.
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat   +5 more
wiley   +1 more source

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