Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer. [PDF]
Chitgaran S+9 more
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Dioscin from smilax china rhizomes inhibits platelet activation and thrombus formation via up-regulating cyclic nucleotides. [PDF]
Lee GH+8 more
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Positive Effects of Caffeine Therapy in a Girl with PDE2A-Related Paroxysmal Dyskinesia. [PDF]
Bernardi K, Thiel M, Koy A.
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Constraint-induced movement therapy combined with mesenchymal stem cell transplantation promotes myelination and functional recovery by inhibiting PRKCD/MEK/ERK pathway in hemiplegic cerebral palsy rats. [PDF]
Guo X+12 more
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Crosstalk between cyclic-di-guanosine monophosphate and the sensor kinase MtrB regulates MtrA-dependent genes, bacterial growth, biofilm formation and lysosomal trafficking of <i>Mycobacterium tuberculosis</i>. [PDF]
Bagchi S+4 more
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Hormonal Regulation of Cyclic Nucleotide Phosphodiesterases* [PDF]
I. Introduction ACOMPLEX array of signals from the extracellular environment regulate many cell processes, including the entry and exit from the mitotic cycle and the induction and maintenance of differentiation (1–3). Cells elaborate these external stimuli via receptors, transducers, and second messengers (4, 5) which control intricate circuits that ...
CONTI M+4 more
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CYCLIC NUCLEOTIDE PHOSPHODIESTERASE AND CYCLIC AMP *
Annals of the New York Academy of Sciences, 1971W. Thompson, M. Appleman
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Cyclic Nucleotides and Phosphodiesterases in Platelets
Thrombosis and Haemostasis, 1999IntroductionIt is now almost 30 years since the discovery that prostaglandin E1 (PGE1) inhibits platelet responses to aggregating agents, together with finding that the effects of this compound are mediated by adenosine 3′, 5′-cyclic monophosphate (cAMP) initiated interest in the physiological and pharmacological regulation of platelet function by ...
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Cyclic Nucleotides Signaling and Phosphodiesterase Inhibition: Defying Alzheimer's Disease.
Current Drug Targets, 2020Defects in brain functions associated with aging and neurodegenerative diseases benefit insignificantly from existing options, suggesting that there is a lack of understanding of pathological mechanisms.
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