Results 281 to 290 of about 76,071 (304)

CYCLIC NUCLEOTIDE PHOSPHODIESTERASES: PHARMACOLOGY, BIOCHEMISTRY AND FUNCTION

Pharmacology & Therapeutics, 1991
This article is a review of cyclic nucleotide phosphodiesterase(s) (CN PDE) from the point of view of the relationships between the newer aspects of the complex enzymology of CN PDE and recent major advances in CN PDE pharmacology. A consolidation of isozyme nomenclature to the proposed family designations is recommended.
openaire   +4 more sources

Cyclic nucleotide phosphodiesterase in silkworm. Developmental change of cyclic AMP and cyclic GMP phosphodiesterases

Biochimica et Biophysica Acta (BBA) - Enzymology, 1975
Changes in theactivities of two cyclic AMP phosphodiesterases (II and III, EC 3.1.4.17) and cyclic GMP phosphodiesterase during development were studied in silkworm, Bombyx mori. The developmental patterns of the activities of the two cyclic AMP phosphodiesterases were similar to each other, but they differed distinctly from that of cyclic GMP ...
openaire   +3 more sources

Can Cyclic Nucleotide Phosphodiesterase Inhibitors Be Drugs for Parkinson’s Disease?

Molecular Neurobiology, 2016
D. N. Nthenge-Ngumbau, K. Mohanakumar
semanticscholar   +1 more source

Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites.

ACS Chemical Biology, 2015
B. L. Howard, Katherine L. Harvey, R. J. Stewart, M. F. Azevedo, B. Crabb, I. Jennings, P. Sanders, D. Manallack, P. Thompson, C. Tonkin, P. Gilson   +10 more
semanticscholar   +1 more source

Cyclic GMP-regulated cyclic nucleotide phosphodiesterases

Cellular Signalling, 1993
Igor P. Udovichenko, Dolores J. Takemoto, Jess Cunnick, Karen Gonzalez   +3 more
openaire   +3 more sources

Multiple cyclic nucleotide phosphodiesterase activities from rat brain.

Biochemistry, 1971
Thompson Wj, Appleman Mm
semanticscholar   +1 more source

Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents.

Pharmacology and Therapeutics, 2006
C. Lugnier
semanticscholar   +1 more source

Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors.

TIPS - Trends in Pharmacological Sciences, 1990
J. Beavo, J. Beavo, D. Reifsnyder, D. Reifsnyder   +3 more
semanticscholar   +1 more source

Cyclic Nucleotide Phosphodiesterases

2004
V.C. Manganiello, E. Degerman
openaire   +1 more source

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes.

Journal of Urology, 1998
Stephen A. Ballard, Clive Gingell, Kim Tang, Leigh A. Turner, Mary E. Price, ALASDAIR M. Naylor   +5 more
semanticscholar   +1 more source