Results 91 to 100 of about 71,552 (319)

Construction of Cyclically Permutable Codes From Cyclic Codes

Proceedings of The 3rd International Conference on Intelligent Systems and Image Processing 2015, 2015
Cyclically permutable codes (CPCs) are important to communication networks, e.g., multiple access collision channels without feedback and frequency-hopping spread spectrum communication channels. A CPC is a block code of length n such that each codeword has full cyclic order n and all codewords are cyclically distinct.
Ting-Ya Yang, Houshou Chen, Kuo-Cheng Chung   +2 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

On the $\operatorname{rix}$ statistic and valley-hopping [PDF]

Discrete Mathematics & Theoretical Computer Science
This paper studies the relationship between the modified Foata$\unicode{x2013}$Strehl action (a.k.a. valley-hopping)$\unicode{x2014}$a group action on permutations used to demonstrate the $\gamma$-positivity of the Eulerian polynomials$\unicode{x2014 ...
Nadia Lafrenière, Yan Zhuang
doaj   +1 more source

Permutability graph of cyclic subgroups

, 2015
Let $G$ be a group. \textit{The permutability graph of cyclic subgroups of $G$}, denoted by $ _c(G)$, is a graph with all the proper cyclic subgroups of $G$ as its vertices and two distinct vertices in $ _c(G)$ are adjacent if and only if the corresponding subgroups permute in $G$.
Rajkumar, R., Devi, P.
openaire   +2 more sources

Periodic Ordered Permutation Groups and Cyclic Orderings

Journal of Combinatorial Theory, Series B, 1995
It is shown that periodic ordered permutation groups satisfying certain extra conditions are very nearly simple. This is applied to several natural examples, such as the following. (i) If \(z\) denotes the map \(x \mapsto x + 1\) on \(\mathbb{R}\), and \(\text{Diff}(\mathbb{R})\) is the group of diffeomorphisms of \(\mathbb{R}\), then \(C_{\text{Diff}(\
Droste, M., Giraudet, M., Macpherson, D.
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Nash implementable domains for the Borda count [PDF]

We characterize the preference domains on which the Borda count satisfies Maskin monotonicity. The basic concept is the notion of a "cyclic permutation domain" which arises by fixing one particular ordering of alternatives and including all its cyclic ...
Puppe, Clemens, Tasnádi, Attila
core   +1 more source

Random and exhaustive generation of permutations and cycles

, 2007
In 1986 S. Sattolo introduced a simple algorithm for uniform random generation of cyclic permutations on a fixed number of symbols. This algorithm is very similar to the standard method for generating a random permutation, but is less well known.
D. Gries, D.E. Knuth, D.E. Knuth, H.M. Mahmoud, M.C. Wilson, Mark C. Wilson, R. Mantaci, S. Sattolo, W. Myrvold   +8 more
core   +3 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source