Results 21 to 30 of about 2,568 (258)

Evaluating the EVENODD Code: Principles, Applications, and Future Prospects in Data Storage Systems [PDF]

ITM Web of Conferences
In modern data storage and transmission, ensuring data integrity and reliability is critical due to potential losses or corruption caused by channel instability and system errors. Check codes have been developed to address these issues, allowing recovery
Deng Jinxiang
doaj   +1 more source

Automatic Recognition and Replacement of Cyclic Redundancy Checks for Program Optimization

IEEE Access
Cyclic redundancy check (CRC) is a fundamental error-detection mechanism widely used in digital networks and storage systems to ensure data integrity. CRC can be implemented in various ways.
Mariam Arutunian, Sevak Sargsyan, Matevos Mehrabyan, Lilit Bareghamyan, Hayk Aslanyan   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Pre-Configured Error Pattern Ordered Statistics Decoding for CRC-Polar Codes

Entropy, 2023
In this paper, we propose a pre-configured error pattern ordered statistics decoding (PEPOSD) algorithm and discuss its application to short cyclic redundancy check (CRC)-polar codes.
Xuanyu Li, Kai Niu, Yuxin Han, Jincheng Dai, Zhiyuan Tan, Zhiheng Guo   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Performance evaluation of INDECT security architecture

Iteckne, 2018
This paper evaluates the performance of the key elements of the security architecture developed by the INDECT project. In particular it first evaluates three different concurrent error detection mechanism (parity check, Berger code, and cyclic redundancy
Petr Machník, Marcin Niemiec, Manuel Urueña, Nikolai Stoianov   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

CRC-aided Multiple Traceback Decoding Algorithm of Spinal Code [PDF]

Jisuanji gongcheng, 2017
In order to improve the decoding efficiency of Spinal code,the beam search and Cyclic Redundancy Check(CRC)decoding are considered as a whole for joint decoding,a CRC-aided multiple traceback decoding algorithm is proposed.The correct decoding route is ...
QU Xiaoxu,YANG Liming,MIAO Quanqiang
doaj   +1 more source