Results 41 to 50 of about 737 (169)

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

LURP1, a SARD1‐regulated protein, coordinates with the helper NLR ADR1 to promote plant immunity

New Phytologist, Volume 251, Issue 5, Page 2852-2866, September 2026.
The working model of LURP1 function in plant immunity. Upon pathogen infection, SARD1/CBP60g promotes the transcription of LURP1 directly. LURP1 likely functions as an adaptor protein that associates with the PRRs–BAK1 complexes at the plasma membrane (PM) while also interacts with the ADR1 family helper NLRs.
Xueru Liu, Weijie Huang, Zhengxi Gong, Chenying Li, Siyu Chen, Shucai Wang, Yuelin Zhang, Xin Li   +7 more
wiley   +1 more source

Generalized Segmented Bit-Flipping Scheme for Successive Cancellation Decoding of Polar Codes With Cyclic Redundancy Check

IEEE Access, 2019
As a new flavor for the successive cancellation decoding of polar codes, bit-flipping technology can be used to improve the frame error rate performance of polar codes at moderate code lengths.
Shibao Li, Yunqiang Deng, Xun Gao, He Li, Lin Guo, Zhenwei Dong   +5 more
doaj   +1 more source

RGF signaling bridges root development and nonlethal thermal stress adaptation

New Phytologist, Volume 251, Issue 5, Page 2656-2671, September 2026.
Nonlethal high temperature inhibits root growth. Summary Roots adapt to growth‐restricting but nonlethal high temperatures. Although lethal heat shock and moderately elevated temperatures have been extensively studied, the effects of nonlethal thermal stress on root development remain unclear.
Yu‐Chun Hsiao, Joon‐Keat Lai, Shiau‐Yu Shiue, Masashi Yamada   +3 more
wiley   +1 more source

A Novel Error Detection due to Joint CRC Aided Denoise-and-Forward Network Coding for Two-Way Relay Channels

The Scientific World Journal, 2014
In wireless two-way (TW) relay channels, denoise-and-forward (DNF) network coding (NC) is a promising technique to achieve spectral efficiency. However, unsuccessful detection at relay severely deteriorates the diversity gain, as well as end-to-end ...
Yulun Cheng, Longxiang Yang
doaj   +1 more source

Improved Polar SCL Decoding by Exploiting the Error Correction Capability of CRC

IEEE Access, 2019
Novel successive cancellation list (SCL) decoding schemes of Polar codes by exploiting the error correction (EC) capability of the cyclic redundancy check (CRC) codes are proposed in this paper.
Xijin Liu, Shaohua Wu, Xiao Xu, Jian Jiao, Qinyu Zhang   +4 more
doaj   +1 more source

Advancing gambogic acid for translational oncology: Redox–proteostasis collapse, multidrug resistance reversal, nanodelivery and biomarker‐guided development

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Gambogic acid exerts anticancer effects through reactive oxygen species‐mediated apoptosis, suppression of nuclear factor kappa B and phosphatidylinositol‐3‐kinase–protein kinase B signalling, multidrug resistance modulation and tumour microenvironment effects.
Uttam Singh Baghel, Kajal Gurow, Geetanjali Mehara, Priyanka Kriplani, Neelam M. Patel, Abhay Sharma, Deeksha Singh, Atamjit Singh, Suchi Dave, Bhawani Singh, Lashyn N. Kiyekbayeva, William N. Setzer, Javad Sharifi‐Rad, Cheryl Grace Pratiwi Rumahorbo, Daniela Calina   +14 more
wiley   +1 more source

Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +4 more
wiley   +1 more source

Tumour‐Derived Extracellular Vesicles Containing dsRNA Induce Degradation of Ribosomal Protein mRNA in Platelets

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
ABSTRACT Extracellular vesicles (EVs) mediate intercellular communication within the tumour microenvironment by carrying cargoes from paracrine parent cells. EVs have attracted great research interest for their ability to carry nucleic acids into recipient cells and modulate cellular functions.
Gaoge Sun, Yuhuan Tao, Zihan Liu, Kaixiang Zhang, Shuai Zuo, Shanwen Chen, Shufang Ning, Tianyi Zhang, Pengyuan Wang, Ying Zhang, Zhi John Lu, Hang Hubert Yin   +11 more
wiley   +1 more source