Results 51 to 60 of about 45,307 (270)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
In this paper, I analyze the evolution of the Latin adverb/discourse marker NUNC and its Old and Modern French equivalents, or and maintenant, markers whose content-level source meanings are in all cases equivalent to English now.
Hansen Maj-Britt Mosegaard
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cyclic Cushing's Disease in the Prepubertal Period—A Case Report and Review of Literature
Background: Cyclic Cushing's disease (CD) has been described in about 15% of adult patients with CD. In the pediatric population, diagnosis of CD is rare and cyclic presentations of the disease are not adequately understood or described.
Anna Wȩdrychowicz +4 more
doaj +1 more source
Milk progesterone as a tool to improve fertility in dairy cows [PDF]
Milk progesterone offers an opportunity to objectively study fertility in dairy cows, in contrast to traditional measures of dairy cow fertility, which in general are highly influenced by on-farm management decisions.
Petersson, Karl-Johan
core
We prove a class of cyclic inequalities including the ones that are related with the positivity of Choi’s maps in matrix algebras.
openaire +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
This paper examines a particular variety of parasitic gap (PG) in English that appears in relative clauses, licensed by extraction from the relativized NP.
Colin P Davis
doaj +2 more sources

