Results 361 to 370 of about 504,196 (405)
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Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
Nature, 1994T. Nobori +5 more
semanticscholar +1 more source
Cyclin dependent kinase (CDK) inhibitors as anticancer drugs.
Bioorganic & Medicinal Chemistry Letters, 2015Concha Sánchez-Martínez +3 more
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Assays for Cyclin-Dependent Kinase Inhibitors [PDF]
, 2003 Tyler Lahusen, Adrian M. Senderowicz
openaire +2 more sources
2004
The cyclin/cyclin-dependent kinase (Cdk) complexes and the Cdk inhibitors (CDKI) are crucial regulators of cell cycle progression in all eukaryotic cells. Using rat cardiac myocytes as a model system, this chapter provides a detailed account of methods that can be employed to measure both cyclin/Cdk activity in cells and the extent of CDKI inhibitory ...
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The cyclin/cyclin-dependent kinase (Cdk) complexes and the Cdk inhibitors (CDKI) are crucial regulators of cell cycle progression in all eukaryotic cells. Using rat cardiac myocytes as a model system, this chapter provides a detailed account of methods that can be employed to measure both cyclin/Cdk activity in cells and the extent of CDKI inhibitory ...
openaire +3 more sources
Trends in kinase drug discovery: targets, indications and inhibitor design
Nature Reviews Drug Discovery, 2021Helgi B Schiöth +2 more
exaly
Kinase drug discovery 20 years after imatinib: progress and future directions
Nature Reviews Drug Discovery, 2021Darren Cross +2 more
exaly
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
Nature, 2006V. Janzen +9 more
semanticscholar +1 more source
Kinase inhibition in autoimmunity and inflammation
Nature Reviews Drug Discovery, 2021Ali A Zarrin +2 more
exaly