Results 111 to 120 of about 4,205,053 (351)

A matter of utility? Rationalising cycling, cycling rationalities

open access: yes, 2015
This paper discusses how dominant policy paradigms promote a ‘utility’ model of transport, prioritising the destruction of distance and the minimisation of time spent travelling.
Aldred, R.
core   +1 more source

Control strategies for integration of electric motor assist and functional electrical stimulation in paraplegic cycling: Utility for exercise testing and mobile cycling [PDF]

open access: yes, 2004
AIM: The aim of this study was to investigate feedback control strategies for integration of electric motor assist and functional electrical stimulation (FES) for paraplegic cycling, with particular focus on development of a testbed for exercise testing
Stone, B.   +13 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Underground Railroad bicycle route : [United States] / Adventure Cycling Association ; production manager, Carla Majernik ; cartography, ACA Routes and Maping Staff ; text, Michael McCoy

open access: yes, 2013
Revision June 2013-Aug. 2014.Other title Mobile, AL to Fulton, MS, 400.5 miles. Fulton, MS to Owensboro, KY, 435 miles. Owensboro, KY to Milford, OH, 373.5 miles. Milford, OH to Erie, PA, 418.5 miles. Erie, PA to Owen Sound, ON, 378 miles.
Adventure Cycling Association, cartographer;
core  

Oral β-hydroxybutyrate salt fails to improve 4-minute cycling performance following submaximal exercise [PDF]

open access: yes, 2017
The purpose of the present study was to examine the effects of an oral β-hydroxybutyrate (BHB) supplement on cycling performance. Using a double-blind, placebo-controlled, crossover design, 12 highly-trained cyclists (mean ± SD: age; 35 ± 8 y, mass; 74.5
Plews, Daniel   +3 more
core  

Cycles and stability

open access: yesJournal of Combinatorial Theory, Series B, 2008
We derive a number of extremal and Ramsey stability results for cycles.
Vladimir Nikiforov 0001   +1 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On cycling in the simplex method of the Transportation Problem [PDF]

open access: yes
This paper shows that cycling of the simplex method for the m×n Transportation Problem where k-1 zero basic variables are leaving and reentering the basis does not occur once it does not occur in the k×k Assignment Problem.
SZWARC, Wlodzimierz
core  

Volcanically driven Hg–C–S cycling and climate change across the Early Permian Artinskian warming

open access: yesCommunications Earth & Environment
Climate change and driving mechanisms of the Late Paleozoic Ice Age, an ideal analogue to the present-day global change, remain controversial. Here we propose a volcanic carbon–sulfur radiative forcing mechanism by investigating the Lower Permian ...
Anbin Wu   +6 more
doaj   +1 more source

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