Results 261 to 270 of about 622,161 (318)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Spatiotemporal Dynamics of the Relative Abundance of Soil Nutrient-Degrading Enzyme-Encoding Genes Across Continental US Ecoregions. [PDF]

Ecol Evol
Jung CG, Gautam S, Song Y, Poorey K, Mishra U.   +4 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Responses of Soil Nitrogen-Cycling Microbial Communities and Functional Potential to Grazing Intensities in Alpine Meadows. [PDF]

Microorganisms
Qie T, Lin D, Fan Q, Sun G, Wang H, Liu Z, Liu X.   +6 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Sweat Electrolyte Profiles During Daily Physical Activities Among Chinese Adults. [PDF]

Nutrients
Chen Y, Liang Y, Lu Z, Zhang Z, Wen W, Zhang C, Liu F, Wang M, Feng M, Qiu J.   +9 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Riding toward inclusion: the journey of adapted cycling. [PDF]

Front Sports Act Living
Sorraghan S, Logan S, Watchorn V, Williams D, Hitch D, Watson JM, Aedy K, Dogra T, Fay P, Haanappel M, Shukla A, Lebeau G, Little J, McKenna J, Townsend K, Anderson KLM.   +15 more
europepmc   +1 more source

History Matters in Solid-State Hydrogen Storage: Hidden State Variables and Pathway-Dependent Reactivity in Mg-Based Hydrides. [PDF]

Molecules
Chen C, Hou Q, Gao L, Ding Z.
europepmc   +1 more source

Yolk-Shell Silicon-Carbon Anodes with Interconnected N-Doped Carbon Networks for Stable Lithium-Ion Storage. [PDF]

Materials (Basel)
Zhou Y, Zhang Y, Zhao Z, Qu Y, Wu J, Ma X, Chang X.   +6 more
europepmc   +1 more source