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Rapid and reversible regulation of cell cycle progression in budding yeast using optogenetics
Koutsoumpa A, Milias-Argeitis A.
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Cyclins, cyclin‐dependent kinases and differentiation
BioEssays, 1997AbstractCyclin‐dependent kinases and their regulatory subunits, the cyclins, are known to regulate progression through the cell cycle. Yet these same proteins are often expressed in non‐cycling, differentiated cells. This review surveys the available information about cyclins and cyclin‐dependent kinases in differentiated cells and explores the ...
Chun Y. Gao, Peggy S. Zelenka
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Trends in Cell Biology, 1992
Cyclins are regulatory subunits of the serine/threonine protein kinases that play key roles in cell cycle control. The roster of known cyclins has expanded significantly in the past year, revealing a large and very diverse family of proteins. Although cyclins were originally characterized by their periodic accumulation during interphase and destruction
Steven I. Reed, Daniel J. Lew
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Cyclins are regulatory subunits of the serine/threonine protein kinases that play key roles in cell cycle control. The roster of known cyclins has expanded significantly in the past year, revealing a large and very diverse family of proteins. Although cyclins were originally characterized by their periodic accumulation during interphase and destruction
Steven I. Reed, Daniel J. Lew
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Molecular Neurobiology, 2020
Development and normal physiology of the nervous system require proliferation and differentiation of stem and progenitor cells in a strictly controlled manner. The number of cells generated depends on the type of cell division, the cell cycle length, and the fraction of cells that exit the cell cycle to become quiescent or differentiate. The underlying
Alice Grison +2 more
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Development and normal physiology of the nervous system require proliferation and differentiation of stem and progenitor cells in a strictly controlled manner. The number of cells generated depends on the type of cell division, the cell cycle length, and the fraction of cells that exit the cell cycle to become quiescent or differentiate. The underlying
Alice Grison +2 more
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Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present
Expert Opinion on Investigational Drugs, 2014Introduction: Intensive efforts, over the last decade, have been made to inhibit the kinase activity of cyclins that act as mediators during cell-cycle progression. Activation of the cyclin D1 oncogene, often by amplification or rearrangement, is a major
Mathew C. Casimiro +3 more
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The International Journal of Biochemistry & Cell Biology, 2004
E-type cyclins (cyclin E1 and cyclin E2) are expressed during the late G1 phase of the cell cycle until the end of the S-phase. The activity of cyclin E is limiting for the passage of cells through the restriction point "R" which marks a "point of no return" for cells entering the division cycle from a resting state or passing from G1 into S-phase ...
Tarik, Möröy, Christoph, Geisen
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E-type cyclins (cyclin E1 and cyclin E2) are expressed during the late G1 phase of the cell cycle until the end of the S-phase. The activity of cyclin E is limiting for the passage of cells through the restriction point "R" which marks a "point of no return" for cells entering the division cycle from a resting state or passing from G1 into S-phase ...
Tarik, Möröy, Christoph, Geisen
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Reviews in Medical Virology, 2000
Cyclins are regulatory subunits of the cyclin-dependent protein kinases (CDKs). Members of this serine-threonine kinase family regulate the progression of cells through the division cycle. Until some years ago, cyclins were presumed to be encoded exclusively by eukaryotic cells.
S, Mittnacht, C, Boshoff
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Cyclins are regulatory subunits of the cyclin-dependent protein kinases (CDKs). Members of this serine-threonine kinase family regulate the progression of cells through the division cycle. Until some years ago, cyclins were presumed to be encoded exclusively by eukaryotic cells.
S, Mittnacht, C, Boshoff
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