Results 261 to 270 of about 831,285 (343)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Cu-catalyzed enantioconvergent oxygen-centered radical cyclization. [PDF]

Chem Sci
Li ZY, Huang CD, Guan CY, Guo HM, Liu LM, Xiao X, Gao B, Ni SF, Mei GJ.   +8 more
europepmc   +1 more source

$sup 235$U--THORIUM FUEL CYCLES IN GRAPHITE MODERATED SYSTEMS. Project DRAGON.

, 1965
J. Blomstrand, J. Schlosser, H. Bruneder, U. Nyffenegger, G. Graziani   +4 more
openalex   +1 more source

Revascularization-Driven Nanozyme Therapy: Disrupting the Vicious Cycle of ROS and Insufficient Vascularization for Chronic Wound Healing [PDF]

Qiao Jiang, Meixia Zhang, Yuqi Yang, Mingzhu Jin, Junlong Zhao, Da Chen, Bo Jiang, Mengfan Li, Jiahao Ma, Jie Li, Jianwei Zhao, Yongquan Qu, Ling Liu, Sanzhong Li, Zhimin Tian   +14 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Exploring the formation of medium-sized cyclic amines within self-assembled yoctoliter inner-spaces. [PDF]

Chem Sci
Ismaiel YA, Rogers D, Gibb BC.
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Total Synthesis of Aconicarmisulfonine A, a Sulfonated Diterpene Alkaloid. [PDF]

J Am Chem Soc
Ning S, Maimone TJ.
europepmc   +1 more source

Incertidumbre, ciclo económico y crisis según el enfoque continuista del pensamiento keynesiano [Uncertainty, economic cycles and economic crises according to the continuism approach of Keynesian thought]

, 2014
Juan Hernández Andréu, Guido Tortorella Expósito   +1 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source