Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]
, 2014 Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core
Thiol-reactive analogues of galanthamine, codeine and morphine as potential probes to interrogate allosteric binding within nAChRs [PDF]
, 2016 Alkaloids including galanthamine (1) and codeine (2) are reported to be positive allosteric modulators of nicotinic acetylcholine receptors (nAChRs) but the binding sites responsible for this activity are not known with certainty.
Balle, Thomas +3 more
core +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Probing the Human Estrogen Receptor-α Binding Requirements for Phenolic Mono- and Di-Hydroxyl Compounds: A Combined Synthesis, Binding and Docking Study [PDF]
, 2014 Various estrogen analogs were synthesized and tested for binding to human ERα using a fluorescence polarization displacement assay. Binding affinity and orientation were also predicted using docking calculations.
Donaldson, William A. +8 more
core +1 more source
INTENSIFICATION OF THE CYCLOHEXANE LIQUID PHASE OXIDATION PROCESS
Тонкие химические технологии, 2018 Liquid-phase oxidation of cyclohexane to cyclohexanol and cyclohexanone was studied in the absence of solvents under an air pressure of 0.5-5 MPa, in the temperature range 115-150 °C, catalyzed by N-hydroxyphthalimide (N-HPI).
A. S. Frolov +5 more
doaj +1 more source
Advances in organic UV filters for sunscreens over the past decade
Photochemistry and Photobiology, EarlyView.Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon +4 more
wiley +1 more source
Synthesis and structure of trans-1,2,3- tris(3-thenoyl)cyclopropane [PDF]
, 1994 The title cyclopropane derivative, C18H12O3S3, was synthesized and its structure investigated by single-crystal X-ray diffraction and spectroscopic methods.
Saba, Antonio
core
The influence of water vapour on the photocatalytic oxidation of cyclohexane in an internally illuminated monolith reactor [PDF]
, 2014 This paper discusses effects of humidity on photocatalytic cyclohexane oxidation performed in an internally illuminated monolith reactor equipped with an immobilised layer of approximately 3 μm titania (Hombikat uv100).
Dijk, Vic H.A. van +2 more
core +3 more sources
Industrial Process and Modern Technical Adaptations for Nylon 6 Monomer Caprolactam: A Mini Review
MedžiagotyraCaprolactam is in high demand in the new materials industry as a monomer for nylon and polyamides. Although the schemes of traditional processes such as hydroxylamine production (hydroxylamine sulphate oxime process, hydroxylamine phosphate oxime process,
Jing HUANG +4 more
doaj +1 more source
2-[(4-Chlorophenyl)(2-phenyl-1H-indol-3-yl)methyl]cyclohexan-1-one
IUCrData, 2016 In the title compound, C27H24ClNO, the indole ring is almost orthogonal to the chlorophenyl ring and the mean plane of the cyclohexanone ring, making a dihedral angles of 82.11 (6) and 89.96 (4)°, respectively.
M. Venkatachalam +4 more
doaj +1 more source