The double protonation of dihapto-coordinated benzene complexes enables dearomatization using aromatic nucleophiles. [PDF]
Nat Commun, 2023 Friedel-Crafts Arylation (the Scholl reaction) is the coupling of two aromatic rings with the aid of a strong Lewis or Brønsted acid. This historically significant C–C bond forming reaction normally leads to aromatic products, often as oligomeric ...
Weatherford-Pratt JT +7 more
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Highly oxygenated cyclohexenes from the leaves of Uvaria grandiflora Roxb. ex Hornem and their cytotoxic and α-glucosidase inhibitory activities. [PDF]
HeliyonPhytochemical investigation of the leaf extract of Uvaria grandiflora Roxb. ex Hornem led to the isolation and identification of two new highly oxygenated cyclohexenes, uvariagrandols A (1) and B (2), together with seven known compounds (3–9).
Suthiphasilp V +13 more
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Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2. [PDF]
Front Pharmacol, 2023 Introduction: Due to its highly aggressiveness and malignancy, glioblastoma (GBM) urgently requires a safe and effective treatment strategy. Zeylenone, a natural polyoxygenated cyclohexenes compound isolated from Uvaria grandiflora, has exhibited ...
Su R +10 more
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Palladium-catalyzed enantioselective β-hydride elimination for the construction of remote stereocenters. [PDF]
Nat CommunThe β-H elimination is a crucial elementary step in transition-metal catalysis, but controlling the stereochemistry of this process has been underdeveloped.
Sun S, Sun S, Zi W.
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Heliyon, 2020 Phytochemical investigations from the flower and leaf extracts of D. cochinchinensis resulted in the isolation and structural elucidation of five new polyoxygenated seco-cyclohexene derivatives, desmoscochinchinenes A-E (1–5), together with 11 known ...
Virayu Suthiphasilp +2 more
exaly +3 more sources
CuI-Zeolite Catalysis for Biaryl Synthesis via Homocoupling Reactions of Phenols or Aryl Boronic Acids. [PDF]
MoleculesDue to the importance of biaryls as natural products, drugs, agrochemicals, dyes, or organic electronic materials, a green alternative biaryl synthesis has been developed based on easy-to-prepare and cheap copper(I)-exchanged zeolite catalysts.
Di X +7 more
europepmc +2 more sources
Crossed Regio‐ and Enantioselective Iron‐Catalyzed [4+2]‐Cycloadditions of Unactivated Dienes [PDF]
Angewandte Chemie - International Edition, 2022 Nicolai Cramer
exaly +2 more sources
Phosphine-Catalyzed [4 + 2] Annulation: Synthesis of Cyclohexenes [PDF]
Journal of the American Chemical Society, 2007 Ohyun Kwon
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Approaches to the Total Synthesis of Conduramines: A Review
SynOpen, 2022 This review reports on the total synthesis of conduramines, which are formally derived from conduritols, mainly containing a trihydroxy aminocyclohexene core.
Hanumantharayappa Bharathkumar +3 more
doaj +1 more source
A new finding in the old Knoevenagel condensation reaction
Results in Chemistry, 2022 Reaction of benzaldehyde (5a) with defined quantities of ethyl cyanoacetate (6) in presence of piperidine was studied. In a neat condition, hexasubstituted cyclohexeneamine (7a) with three ester substituents was formed along with ethyl acrylate (9a ...
Attimogee Shivamurthy Harisha +5 more
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