Results 101 to 110 of about 7,352 (256)

Phenyl Sulfones: A Route to a Diverse Family of Trisubstituted Cyclohexenes from Three Independent Nucleophilic Additions. [PDF]

open access: yesJ Am Chem Soc, 2022
Simpson SR   +9 more
europepmc   +1 more source

Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis

open access: yesAsian Journal of Organic Chemistry, Volume 14, Issue 8, August 2025.
This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley   +1 more source

Advances in Ligand‐Driven Pd‐Catalyzed C─H Functionalizations: Recent Insights and Updates

open access: yesChemCatChem, Volume 17, Issue 15, August 7, 2025.
The most significant advances in ligand‐driven Pd‐catalyzed organic synthesis over the past two years are presented. Processes involving C─H activation of substrates, avoiding their prefunctionalization are illustrated. Both the activity and selectivity of the catalyst depend on the design of the ligands (pyridones, pyridines, amino acids, phosphines ...
Jesús Moradell   +3 more
wiley   +1 more source

Structures of Listeria monocytogenes MenD in ThDP‐bound and in‐crystallo captured intermediate I‐bound forms

open access: yesActa Crystallographica Section F, Volume 81, Issue 8, Page 348-357, August 2025.
Here, we report structures of the ThDP‐dependent enzyme MenD (SEPHCHC synthase) from L. monocytogenes in its ThDP cofactor‐bound and intermediate I‐bound forms. Comparisons with an apo form previously deposited in the PDB revealed that this MenD adopts a typical three‐domain ThDP‐dependent fold, with lower levels of disorder associated with closing of ...
Michelle Bailey   +5 more
wiley   +1 more source

A high‐resolution data set of fatty acid‐binding protein structures. III. Unexpectedly high occurrence of wrong ligands

open access: yesActa Crystallographica Section D, Volume 81, Issue 8, Page 451-464, August 2025.
Very high‐resolution fatty acid‐binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially overlooked problem in other, lower resolution, crystal structures of protein–ligand complexes, it has repercussions for any study using such structures ...
Andreas Ehler   +4 more
wiley   +1 more source

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