Results 101 to 110 of about 378,238 (343)
Arthritis Care &Research, Accepted Article.Objectives Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition, with widely varying global prevalence estimates. Frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the US or UK at 19‐39 per 100,000 as opposed to 65‐97 per 100,000.
Lucinda Roper +7 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns +2 more
wiley +1 more source
Pregnancy-associated breast cancer - Special features in diagnosis and treatment [PDF]
, 2006 For obvious psychological reasons it is difficult to associate pregnancy - a life-giving period of our existence with life-threatening malignancies. Symptoms pointing to malignancy are often ignored by both patients and physicians, and this, together ...
Bauerfeind, I. +7 more
core +1 more source
Haematologica, 2017 Severe graft-versus-host disease is a major barrier for non-T-cell-depleted haploidentical stem cell transplantation. There is no consensus on the optimal graft-versus-host disease prophylaxis.
A. Ruggeri +17 more
semanticscholar +1 more source
Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation
Advanced Science, EarlyView.FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin +14 more
wiley +1 more source
Outcomes of haploidentical stem cell transplantation for chronic lymphocytic leukemia: a retrospective study on behalf of the chronic malignancies working party of the EBMT [PDF]
, 2017 Allogeneic hematopoietic stem cell transplantation (HCT) may result in long-term disease control in high-risk chronic lymphocytic leukemia (CLL). Recently, haploidentical HCT is gaining interest because of better outcomes with post-transplantation ...
Beelen, Dietrich +23 more
core +1 more source
فصلنامه دانشگاه علوم پزشکی جهرم, 2014 Introduction: Cyclophosphamide, anti-cancer drugs which are used in chemotherapy. Purpose of this study was to investigate the effects of Tribulus terrestris extract on sex hormones in male rats after treatment with cyclophosphamide. material and Method:
najme rajabi, hojatollah karimi jashni
doaj
Frontiers in Bioscience-ScholarBackground: Approximately 75% of drug metabolism in clinical settings is attributed to cytochrome P450 enzymes. This study aimed to assess the effects of the CYP3A4*1B and CYP3A5*3 genetic variations on the clinical results of ...
Heba M. Elmaraghy +7 more
doaj +1 more source
Advanced Science, EarlyView.A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun +23 more
wiley +1 more source
The protective effects of Allium ampeloprasum Subsp Iranicum on cyclophosphamide-induced immunosuppression in NMRI Mice: A promising natural immunomodulator [PDF]
Avicenna Journal of PhytomedicineObjective: Cyclophosphamide (CTX) is an effective anticancer drug, but toxic effects against normal human tissues are its dose-limiting drawback. The aim of this research was to investigate the in vivo immunomodulatory activities of Allium ampeloprasum ...
Fateme Abedi +2 more
doaj +1 more source