Results 101 to 110 of about 154,825 (291)

Optimizing Brentuximab Vedotin Dosing in Pediatric Patients with Advanced Hodgkin Lymphoma: A Population Pharmacokinetic and Exposure‐Response Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pediatric patients with advanced‐stage newly diagnosed Hodgkin lymphoma (HL) were treated with brentuximab vedotin (BV) combined with adriamycin, vinblastine, and dacarbazine (A + AVD). Weight‐based BV dosing is employed in adult patients, while both body weight‐ and body surface area (BSA)‐based dosing are used in pediatric patients.
Xiaofei Zhou   +4 more
wiley   +1 more source

A Case Series and Literature Review of Angiosarcoma With Malignant Effusion—A Challenging Cytologic Diagnosis With Dire Prognostic Implications

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam   +3 more
wiley   +1 more source

Role of RNA modifications in carcinogenesis and carcinogen damage response

open access: yesMolecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023
Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese   +2 more
wiley   +1 more source

Recombinant Oncolytic Adenovirus Combined with Cyclophosphamide Induces Synergy in the Treatment of Breast Cancer in vitro and in vivo

open access: yesCancer Management and Research, 2022
Jing Wang,1 Shuting Zuo,1 Yan Zhang,1 Shanzhi Li,2 Ying Shi,1 Tonghua Du,1 Jicheng Han,2 Ningyi Jin,2– 4 Yiquan Li,2 Xiao Li2,3 1Department of Breast Surgery, The Second Hospital of Jilin University, Changchun, 130000, People’s Republic of China ...
Wang J   +9 more
doaj  

Chromosome polyploidization in human leukocyte cultures treated with streptonigrin and cyclophosphamide [PDF]

open access: bronze, 1967
Carlos E. Nasjleti, Herbert H. Spencer
openalex   +1 more source

Clinical evaluation and outcome in heart failure patients receiving chemotherapy with different anti‐cancer agents

open access: yesESC Heart Failure, EarlyView.
Abstract Background The optimal strategy for modern chemotherapy should be based on a comprehensive approach for cancer patients with cardiovascular diseases. Therefore, cardio‐oncology has received increasing attention owing to the cardiotoxic effects of anti‐cancer therapies.
Tomiko Sunaga   +7 more
wiley   +1 more source

Evaluation of a high dose cyclophosphamide regimen in childhood tumors [PDF]

open access: bronze, 1969
Jerry Z. Finklestein   +2 more
openalex   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal   +14 more
wiley   +1 more source

Cerebellar medulloblastoma.Chemotherapeutic remission with vincristine cyclophosphamide and methotrexate [PDF]

open access: bronze, 1968
Sumner Hagler, Z Currimbhoy, M Tinsley
openalex   +1 more source

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