Results 271 to 280 of about 257,826 (338)

Robust CAR T‐cell expansion and superior outcomes in DLBCL patients in complete response at infusion

open access: yesBritish Journal of Haematology, EarlyView.
In this study, CAR T‐cell expansion and persistence were found to be comparable between CR and non‐CR groups, regardless of the co‐stimulatory domain (CD28 or 4‐1BB) or product used. Furthermore, peripheral blood kinetics—including absolute counts and proportions of total, CD4+ and CD8+ CAR T cells—showed no significant differences between the two ...
Ryo Hanajiri   +11 more
wiley   +1 more source

Transcriptome analysis to decipher the molecular underpinnings of response to treatment in systemic lupus erythematosus. [PDF]

open access: yesRMD Open
Garantziotis P   +14 more
europepmc   +1 more source

Copanlisib in combination with rituximab and bendamustine for transplant‐ineligible relapsed/refractory diffuse large B‐cell lymphoma patients: Results from the phase II multicentre FIL Copa‐BR trial from Fondazione Italiana Linfomi (FIL)

open access: yesBritish Journal of Haematology, EarlyView.
A phase II, single‐arm, multicentre trial was conducted by Fondazione Italiana Linfomi (FIL) to investigate the combination of copanlisib plus rituximab and bendamustine (copa‐BR) in transplant‐ and chimeric antigen receptor (CAR)‐T‐ineligible relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL). Thirty‐seven patients were enrolled.
Mattia Novo   +24 more
wiley   +1 more source

Real-World Outcomes of PET-Adapted Treatment for Classic Hodgkin's Lymphoma: A Study From a Single Tertiary Care Center. [PDF]

open access: yesCureus
Iftikhar I   +8 more
europepmc   +1 more source

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou   +4 more
wiley   +1 more source

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