Results 81 to 90 of about 1,056 (157)

Sustained Remission in a Case of Lupus Nephritis with Cyclosporin Therapy

Saudi Journal of Kidney Diseases and Transplantation, 2001
Systemic lupus erythematosus (SLE) in severe form still presents a major therapeutic challenge. Aggressive treatment of severe renal lesions has improved the prognosis of renal disease over the last decade.
Rabbani Malik, Shah Syed, Ahmad Aasim
doaj  

Olfactory Ensheathing Cell Transplantation Combined With Electrical Epidural Stimulation as a Long‐Term Treatment for Severe Spinal Cord Injury in Female Fischer 344 Rats

European Journal of Neuroscience, Volume 64, Issue 4, August 2026.
This study combined two promising therapies, olfactory ensheathing cell (OEC) transplantation and electrical epidural stimulation, to help reestablish circuit connectivity following a complete, midthoracic spinal cord transection in inbred Fischer 344 rats (A, B).
Kaitlin L. Ingraham Dixie, Alexa M. Tierno, Michael A. Thornton, Mahlet A. Mekonnen, Erica A. Dale, Hui Zhong, V. Reggie Edgerton, Patricia E. Phelps   +7 more
wiley   +1 more source

Functional, Volumetric, and Growth Outcomes After Pediatric Bilateral Lung Transplantation

Pediatric Transplantation, Volume 30, Issue 8, August 2026.
Pediatric bilateral lung transplantation achieved durable functional recovery, catch‐up somatic growth, and comparable postoperative lung volumetric adaptation across graft types, supporting the feasibility of size‐reduced transplantation regardless of recipient age.
Seon Yong Bae, Samina Park, Dae Hyeon Kim, Taeyoung Yun, Ji Hyeon Park, Bubse Na, Kwon Joong Na, Hyun Joo Lee, Ji Soo Park, Dong In Suh, Jimyung Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim   +13 more
wiley   +1 more source

RIPK4 Downregulation Reduces ABCG2 Expression, Increasing BRAF-Mutated Melanoma Cell Susceptibility to Cisplatin- and Doxorubicin-Induced Apoptosis

Biomolecules
Melanoma cells remain resistant to chemotherapy with cisplatin (CisPt) and doxorubicin (DOX). The abnormal expression of Receptor-Interacting Protein Kinase 4 (RIPK4) in certain melanomas contributes to tumour growth through the NFκB and Wnt/β-catenin ...
Bartlomiej Olajossy, Norbert Wronski, Ewelina Madej, Joanna Komperda, Małgorzata Szczygieł, Agnieszka Wolnicka-Glubisz   +5 more
doaj   +1 more source

Haemodynamic responses to small muscle mass exercise before and after lung transplantation in end‐stage chronic obstructive pulmonary disease

Experimental Physiology, Volume 111, Issue 8, Page 3604-3619, 1 August 2026.
Abstract Cardiovascular control during exercise is impaired in chronic obstructive pulmonary disease (COPD). The central cardiopulmonary pathologies in COPD might drive the local muscle vascular abnormalities. We hypothesised that contracting muscle perfusion and O2 utilisation improve after lung transplantation (LTx) in COPD.
Camilla Koch Ryrsø, Thomas Kromann Lund, Pia Thaning, Lasse Gliemann, Michael Perch, Jacob Peter Hartmann, Ida Kær Thorsen, Gregers Winding Munch, Stefan P. Mortensen, Ylva Hellsten, Ronan M. G. Berg, Ulrik Winning Iepsen   +11 more
wiley   +1 more source

Norepinephrine alleviates cyclosporin A-induced nephrotoxicity by enhancing the expression of SFRP1

Open Medicine, 2023
Sun Huaibin, Peng Zhiguo, Liu Kao, Liu Shengli   +3 more
doaj   +1 more source

Cyclosporin-induced remission in an infant with alkylating agents-resistant nephrotic syndrome. A case report

The Turkish Journal of Pediatrics, 1995
The efficacy of cyclosporin-A, a potent immunosuppressive agent, has not been clearly proven in the management of childhood nephrotic syndrome. The occurrence of early relapse as the dose of cyclosporin is tapered or as soon as the drug is stopped
G G Yilmaz, A G Güven
doaj  

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, Volume 604, Issue 16, Page 6659-6674, 15 August 2026.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

A Study of arbutin protective effect on cyclosporin A-induced oxidative damage

Caspian Journal of Internal Medicine, 2015
Background: Cyclosporine A (CsA) is a potent immunosuppressant drug with therapeutic and toxic actions. The use of CsA is limited by its toxicity. Several researchers had proposed that oxidative stress could play an important role in CsA-induced toxicity.
Fatemeh Khadir, Mahdi Pouramir, Gholamali Joorsaraie, Farideh Feizi, Hadi Sorkhi, Fatemeh Yousefi   +5 more
doaj  

Study on Cyclosporin A in intervening the progress of IgA nephropathy

Linchuang shenzangbing zazhi, 2016
Objective To study the effect of cyclosporin A in intervening the progress of IgA nephropathy.Methods 154 selected patients with progressive IgA nephropathy treated in the hospital from April 2012 to March 2016 were randomly divided into control group in
LU Fa-ju, CHEN Yong-jian, YANG Lei
doaj