Functional And Structural Consequences Of Nine Cyp21a2 Mutations Ranging From Very Mild To Severe Effects [PDF]
, 2017 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)We present the functional and structural effects of seven novel (p.Leu12Met, p.Arg16Cys, p.Ser101Asn, p.Ser202Gly, p.Pro267Leu, p.Gln389 Ala391del, and p.Thr450Met) and two previously reported ...
Ana Leticia +11 more
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Structural and Functional Evaluation of Steroidogenic Cytochrome P450 Enzymes [PDF]
, 2015 Cytochromes P450 (CYP450) are heme-containing monooxygenase enzymes that perform a variety of functions in humans, including xenobiotic metabolism and the production of endogenous signaling molecules.
Petrunak, Elyse Marie
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Alta freqüência da mutação Q318X em pacientes com hiperplasia adrenal congênita por deficiência da 21-hidroxilase no nordeste do Brasil [PDF]
OBJETIVES: Deficiency of 21-hydroxylase is the most common form of congenital adrenal hyperplasia (CAH-21OH). The aim of this study was to determine, by allele-specific PCR, the frequency of microconversions of the CYP21A2, in sixteen patients with the ...
AGUIAR-OLIVEIRA, Manuel H. +4 more
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Functional Maturation of the Primate Fetal Adrenal in Vivo: 3. Specific Zonal Localization and Developmental Regulation of CYP21A2 (P450c21) and CYP11B1/CYP11B2 (P450c11/Aldosterone Synthase) Lead to Integrated Concept of Zonal and Temporal Steroid Biosynthesis [PDF]
, 1998 C. L. Coulter
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Phenotype and genotype correlation of the microconversion from the CYP21A1P to the CYP21A2 gene in congenital adrenal hyperplasia [PDF]
, 2003 Natália Torres +5 more
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Avaliação dos critérios diagnósticos hormonais da forma não clássica da deficiência da 21-hidroxilase através do estudo molecular do gene CYP21A2 [PDF]
, 2003 Fernanda A. Correa +1 more
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Bioactivity of Curcumin on the Cytochrome P450 Enzymes of the Steroidogenic Pathway. [PDF]
, 2019 Turmeric, a popular ingredient in the cuisine of many Asian countries, comes from the roots of the Curcuma longa and is known for its use in Chinese and Ayurvedic medicine.
Pandey, Amit Vikram +2 more
core +1 more source
Gender Role Behavior, Sexuality, and Psychosocial Adaptation in Women with Congenital Adrenal Hyperplasia due toCYP21A2Deficiency [PDF]
, 2009 Louise Frisén +9 more
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DNA methylation profiling of the human major histocompatibility complex: A pilot study for the Human Epigenome Project [PDF]
, 2004 The Human Epigenome Project aims to identify, catalogue, and interpret genome-wide DNA methylation phenomena. Occurring naturally on cytosine bases at cytosine-guanine dinucleotides, DNA methylation is intimately involved in diverse biological processes ...
Andrews, TD +13 more
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