Results 231 to 240 of about 37,178 (276)

Investigation of the regulatory effects of tea polyphenols on CYP450s in HepG2 cells. [PDF]

Front Nutr
Zuo D, Ren H, Ren Z, Chen J, Wang F, Zhang Z, Sun H.   +6 more
europepmc   +1 more source

Identification and validation of icaritin-associated prognostic genes in hepatocellular carcinoma through network pharmacology, bioinformatics analysis, and cellular experiments. [PDF]

Front Immunol
Shi Y, Bai Y, Wu J, Yu Y, Yang X, Yang H, Jian W, Qing J.   +7 more
europepmc   +1 more source

Analysis of CYP2C9 promotor variations and possible links to the CYP2C9 2 and CYP2C9 3 exon variants.

, 2018
Schubert, C., Cubic, I., Kirchheiner, Julia, Brockmoeller, Juergen, Roots, Ivar   +4 more
openaire   +1 more source

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. [PDF]

Genes (Basel)
Kalak M, Brylak-Błaszków A, Błaszków Ł, Kalak T.   +3 more
europepmc   +1 more source

Self-Reported Pharmacogenetic Medication Use in the Our Future Health Cohort. [PDF]

Clin Transl Sci
Dixon P, Newman WG, Sharma V, McDermott JH, Wright Drakesmith C.   +4 more
europepmc   +1 more source

Exploring the anti-diabetic potential of peimisine through bioinformatics analysis and <i>in vitro</i> studies. [PDF]

Front Pharmacol
Feng X, Jin J, Ye X, Wu J, Yang B, He Q, Luo P, Lu J, Yang X.   +8 more
europepmc   +1 more source

Factors affecting CYP2C9-mediated metabolism

, 2019
openaire   +2 more sources

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CATALYTIC ROLES OF CYP2C9 AND ITS VARIANTS (CYP2C9*2 AND CYP2C9*3) IN LORNOXICAM 5′-HYDROXYLATION

Drug Metabolism and Disposition, 2004
The effects of allelic variants of CYP2C9 (CYP2C9*2 and CYP2C9*3) on lornoxicam 5'-hydroxylation were studied using the corresponding variant protein expressed in baculovirus-infected insect cells and human liver microsomes of known genotypes of CYP2C9.
Izumi, Iida, Atsunori, Miyata, Masayuki, Arai, Mitsuyo, Hirota, Masayuki, Akimoto, Shohei, Higuchi, Kaoru, Kobayashi, Kan, Chiba   +7 more
openaire   +2 more sources

An identification and functional evaluation of a novel CYP2C9 variant CYP2C9*62

Chemico-Biological Interactions, 2020
Warfarin is the most commonly used anticoagulant in the clinical treatment of thromboembolic diseases. The dose of warfarin varies significantly within populations, and the dose is closely related to the genetic polymorphisms of the CYP2C9 and VKORC1 genes.
Hao, Chen, Da-Peng, Dai, Shan, Zhou, Jian, Liu, Shuang-Hu, Wang, Hua-Lan, Wu, Quan, Zhou, Pei-Wu, Geng, Jia, Chong, You, Lü, Jian-Ping, Cai, Jie-Fu, Yang   +11 more
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ROLE OF CYP2C9 AND ITS VARIANTS (CYP2C9*3 AND CYP2C9*13) IN THE METABOLISM OF LORNOXICAM IN HUMANS

Drug Metabolism and Disposition, 2005
CYP2C9 is an important member of the cytochrome P450 enzyme superfamily with some 12 CYP2C9 alleles (*1-*12) being previously reported. Recently, we identified a new CYP2C9 allele with a Leu90Pro mutation in a Chinese poor metabolizer of lornoxicam [Si D, Guo Y, Zhang Y, Yang L, Zhou H, and Zhong D (2004) Pharmacogenetics 14:465-469].
Yingjie, Guo, Yifan, Zhang, Ying, Wang, Xiaoyan, Chen, Dayong, Si, Dafang, Zhong, J Paul, Fawcett, Hui, Zhou   +7 more
openaire   +2 more sources