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Results 111 to 120 of about 15,566 (231)

Analysis of CYP3A4*1B and CYP3A5*3 polymorphisms in population of Bosnia and Herzegovina [PDF]

Medicinski Glasnik, 2011
Aim Differences in the frequency of distribution of the cytochromeP450 (CYP) allelic variants have been demonstrated between distinct ethnic groups, contributing to observed interindividual variation in drug response. In this study we determined, for the
Sabina Semiz +8 more
doaj

Effect of CYP3A5 genotypes on pharmacokinetic of tacrolimus in colombian liver transplant patients

Frontiers in Pharmacology
BackgroundPrevious studies have reported a reduced tacrolimus dose-adjusted exposure in individuals expressing the CYP3A5*1 allele (rs 776746). However, information regarding Colombian liver transplantation patients is scarce.
Erica Fernanda Lindarte +8 more
doaj +1 more source

The Genetic Polymorphisms of CYP3A4*1G and CYP3A5*3 in Javanese Indonesian Population

Journal of Tropical Life Science
Polymorphisms of CYP3A4*1G and CYP3A5*3 affect the pharmacokinetic profile of various drugs, e.g., fentanyl, tacrolimus, diltiazem, simvastatin. Tetra-primer amplification refractory mutation system-polymerase chain (ARMS-PCR) is a simple and economical ...
Sarah Atmaja +5 more
doaj +1 more source

The Tacrolimus Metabolism Rate Influences Renal Function after Kidney Transplantation

, 2014
The effective calcineurin inhibitor (CNI) tacrolimus (Tac) is an integral part of the standard immunosuppressive regimen after renal transplantation (RTx).
Fortmann, C. (Christian) +10 more
core +1 more source

Ð•Ð¤Ð•ÐšÐ¢Ð˜ ÐÐ CYP3A4 Ð“Ð•ÐÐ•Ð¢Ð¡ÐšÐ˜ ÐŸÐžÐ›Ð˜ÐœÐžÐ Ð¤Ð˜Ð—ÐÐœ Ð’Ð Ð— ÐŸÐžÐ¡Ð¢ÐžÐŸÐ•Ð ÐÐ¢Ð˜Ð’ÐÐÐ¢Ð ÐŸÐžÐ¢Ð ÐžÐ¨Ð£Ð’ÐÐ§ÐšÐ ÐÐ Ð¤Ð•ÐÐ¢ÐÐÐ˜Ð› ÐŸÐ Ð˜ Ð¢Ð Ð•Ð¢ÐœÐÐ ÐÐ ÐŸÐžÐ¡Ð¢ÐžÐŸÐ•Ð ÐÐ¢Ð˜Ð’ÐÐÐ¢Ð Ð‘ÐžÐ›ÐšÐ [PDF]

CYP3A5 Substrate [PDF]

, 2020
openaire +1 more source

Impact of CYP3A5 Polymorphisms on Pediatric Asthma Outcomes

International Journal of Molecular Sciences
Genetic variation among inhaled corticosteroid (ICS)-metabolizing enzymes may affect asthma control, but evidence is limited. This study tested the hypothesis that single-nucleotide polymorphisms (SNPs) in Cytochrome P450 3A5 (CYP3A5) would affect asthma outcomes.
Flory L. Nkoy +6 more
openaire +2 more sources

Interaction between tacrolimus and calcium channel blockers based on CYP3A5 genotype in Chinese renal transplant recipients

Frontiers in Pharmacology
ObjectiveTo investigate the effect of calcium channel blockers (CCBs) on tacrolimus blood concentrations in renal transplant recipients with different CYP3A5 genotypes.MethodsThis retrospective cohort study included renal transplant recipients receiving ...
Huiying Zong +10 more
doaj +1 more source

An assessment on cinematic composition, narrative structure and semiotics in animated films: a case study of Filem Negara Malaysia’s anthropomorphic animal folktales (Sang Kancil: the animated series) / Azahar Harun [PDF]

, 2013
This study concerns the anthropomorphic animal folktale namely Sang Kancil: The Animated Series (SKTAS) produced by Filem Negara Malaysia (National Film Department) during the late 1970s and early 1980s.
Harun, Azahar
core

CYP3A5 Inhibitor [PDF]

, 2020
openaire +1 more source

tacrolimus
pharmacogenetics
cyp3a4

medicine
pharmacology
therapeutics

abcb1
snp
renal transplantation