DiagnosticsBackground/Objectives: Our previous retrospective single-center cohort study found, at 3-year follow-up, a trend toward low tacrolimus trough levels and an increased risk of de novo donor-specific anti-HLA antibodies (DSAs) and of antibody-mediated ...
Kristina Schönfelder +8 more
doaj +1 more source
Administration of Third-Party Mesenchymal Stromal Cells at the Time of Kidney Transplantation: Interim Safety Analysis at One-Year Follow-Up [PDF]
, 2017 Mesenchymal stromal cells (MSC)-based therapy has been proposed in kidney transplantation (KTx). We report on the 1-year follow-up of an open-label phase I trial using MSC in KTx.
BAUDOUX, Etienne +9 more
core
The role of CYP3A5 polymorphism and dose adjustments following conversion of twice-daily to once-daily tacrolimus in renal transplant recipients [PDF]
, 2016 Alina S. R Zaltzman +5 more
core +1 more source
Pharmacogenetic: screening relevant polymorphisms on antiretroviral therapy in a HIV Portuguese population [PDF]
, 2015 Poster presented at the 15th European AIDS Conference. Barcelona, 21-24 October 2015"Several factors cause heterogeneity of response to antiretroviral therapy.
Cruz, J. P. +5 more
core
Analysis of CYP3A5*3 and CYP3A5*6 gene polymorphisms in Indian chronic myeloid leukemia patients.
Asian Pacific journal of cancer prevention : APJCP, 2011 CYP3A5 is a member of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormones. CYP3A5*3 and CYP3A5*6 polymorphisms exhibit inter-individual differences in CYP3A5 expression. The CYP3A5*3 allele (A6986G transition in intron 3) results in loss of CYP3A5 expression and the CYP3A5*6 allele (G14690A transition in exon 2 ...
K, Sailaja +3 more
openaire +1 more source
Effect of CYP3A4∗1G and CYP3A5∗3 Polymorphisms on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Healthy Chinese Subjects [PDF]
, 2017 Liyan Miao +5 more
core +1 more source
Analysis of single-nucleotide polymorphisms (SNPs) in human CYP3A4 and CYP3A5 genes: potential implications for the metabolism of HIV drugs [PDF]
, 2014 core +1 more source
Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models [PDF]
, 2007 Michaela Vossen +5 more
core +1 more source