Results 131 to 140 of about 994,040 (390)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Hepatic Hydatid Disease Causing Gastric Ulcer as a Rare Complication

open access: yes대한영상의학회지, 2019
Hydatid disease in humans is a parasitic disease typically caused by the larvae of Echinococcus granulosus. Although the disease can occur in any body part, it most frequently affects the liver.
Eunae Cho, Sang Soo Shin, Ga Eon Kim
doaj   +1 more source

Arachnoid cyst in a patient with psychosis: Case report

open access: yesAnnals of General Psychiatry, 2007
BackgroundThe aetiology of a psychotic disturbance can be due to a functional or organic condition. Organic aetiologies are diverse and encompass organ failures, infections, nutritional deficiencies and space-occupying lesions.
J. D. da Silva   +5 more
semanticscholar   +1 more source

Rupture of a giant cardiac hydatid cyst in the left ventricular free wall: successful surgical management of a rare entity [PDF]

open access: yes
Hydatid cyst of heart is a rare but potentially fatal site of pathology, especially left ventricular free wall. We managed a successful surgical treatment on a case of a 24 year old man who had a giant cardiac hydatid cyst (71 x 64 mm) that ruptured left
حسن پور, محمد   +6 more
core  

Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. [PDF]

open access: yes, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disease that leads to renal failure in the majority of patients. The very first pharmacological treatment, tolvaptan, received Food and Drug Administration approval in 2018 ...
Bourgeois, Bryan C   +4 more
core   +1 more source

Comparison of the diagnostic accuracy of three current guidelines for the evaluation of asymptomatic pancreatic cystic neoplasms. [PDF]

open access: yes, 2017
Asymptomatic pancreatic cysts are a common clinical problem but only a minority of these cases progress to cancer. Our aim was to compare the accuracy to detect malignancy of the 2015 American Gastroenterological Association (AGA), the 2012 International
Aslanian, Harry   +17 more
core   +2 more sources

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Type II Toxoplasma gondii KU80 Knockout Strains Enable Functional Analysis of Genes Required for Cyst Development and Latent Infection

open access: yesEukaryotic Cell, 2011
Type II Toxoplasma gondii KU80 knockouts (Δku80) deficient in nonhomologous end joining were developed to delete the dominant pathway mediating random integration of targeting episomes.
B. A. Fox   +8 more
semanticscholar   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Aneurysmal bone cyst: a review of 150 patients.

open access: yesJournal of Clinical Oncology, 2005
PURPOSE We have reviewed a series of 150 aneurysmal bone cysts treated over the last 20 years. PATIENTS AND METHODS The lesions were principally located in the tibia, femur, pelvis, humerus, and spine and, in most cases, presented the imaging ...
H. Mankin   +4 more
semanticscholar   +1 more source

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