Results 181 to 190 of about 890,191 (359)

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li   +8 more
wiley   +1 more source

Dental outcomes following treatment of pediatric odontogenic cysts: an 18-year retrospective analysis. [PDF]

open access: yesBMC Oral Health
Onat Kayıkcı S   +4 more
europepmc   +1 more source

miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
V. Patel   +6 more
semanticscholar   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao   +20 more
wiley   +1 more source

Cyst [PDF]

open access: yes, 2011
openaire   +1 more source

Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease.

open access: yesJournal of Clinical Investigation, 2013
Xia Zhou   +5 more
semanticscholar   +1 more source

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