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Mediastinal cysts are mostly congenital, but rarely, infections and malignancies can cause cystic degeneration of enlarged mediastinal lymph nodes. Diagnosis is challenging as the presenting symptoms are nonspecific.
Bharath A Chhabria+6 more
doaj +1 more source
Resection of a colloid adenocarcinoma of the lung: A case report
Colloid adenocarcinoma of the lung is a rare subtype of lung adenocarcinoma, accounting for only about 0.24% of lung cancers. Because of its rarity, long‐term postoperative prognostic reports are limited.
Yuya Kogita+4 more
doaj +1 more source
Endoscopy-assisted removal through combined lower and middle meatotomies of an ectopic upper third molar in the sinus associated with a dentigerous cyst [PDF]
The aim of this case report is to present an original conservative technique for the transnasal endoscopy-assisted extraction of an ectopic upper third molar associated with a dentigerous cyst occupying the whole maxillary sinus by means of combined ...
Borsetto, D.+3 more
core +2 more sources
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. [PDF]
Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disease that leads to renal failure in the majority of patients. The very first pharmacological treatment, tolvaptan, received Food and Drug Administration approval in 2018 ...
Bourgeois, Bryan C+4 more
core +1 more source
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain+3 more
wiley +1 more source
SummaryTwenty-six patients with Baker's cysts have been observed in the period January 1963 to May 1964. Swelling, redness, tenderness and pain in the leg below the cyst was noticed in 11 patients. Seven of these had anti-coagulation treatment before admission.
openaire +4 more sources