Results 61 to 70 of about 21,617 (180)

Does Surgical Approach Influence Benchmark Attainment in Intrahepatic Cholangiocarcinoma?

World Journal of Surgery, Volume 50, Issue 9, Page 2714-2725, September 2026.
Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy with rising incidence and poor prognosis. Surgical resection remains the only curative option, with outcomes driven by R0 margins and lymphadenectomy (LND). While open liver resection (OLR) is standard, laparoscopic (LLR) and robotic liver resection (RLR) are increasingly used, with concerns ...
Delphine Gastineau, Claire Goumard, Alexandre Doussot, Marc‐Antoine Allard, Raphael Venezia, Serena Langella, Guillaume Millet, Ruth Bustamante, Christian Hobeika, Rami Rhaiem, Stylianos Tzedakis, Heithem Jeddou, Bastien Le Floch, Alain Valverde, Nicolas Peru, Patrick Pessaux, Fabio Giannone, Jean Yves Mabrut, Kayvan Mohkam, Antonio Sa Cunha, Chady Salloum, Pierre Yves Blanc, Bertrand Le Roy, Takayuki Kawai, Olivier Farges, Stefan Hofmeyr, David Fuks, Stéphanie Truant, Daniel Cherqui, Alessandro Ferrero, Emmanuel Boleslawski, Jean‐Marc Regimbeau, Eric Vibert, Daniele Sommacale, Olivier Soubrane, Olivier Scatton, Alexis Laurent, Raffaele Brustia, on the behalf of the AFC‐ICC‐2009, AFC‐LLR‐2018, PRS‐2019 and FRIES‐ACHBPT‐2024 Study group   +40 more
wiley   +1 more source

KAT6A–inhibitor co‐crystal structures: tackling a challenging crystallization target via two alternative approaches

Acta Crystallographica Section D, Volume 82, Issue 9, Page 1111-1124, September 2026.
We report a novel cysteine‐to‐serine surface‐mutation approach to determine co‐crystal structures of KAT6A with small‐molecule inhibitors and compare it with the previously published MYSTcryst approach which uses mutated KAT8 as a surrogate for KAT6A.
Vera Puetter, Léa Bouché, Katrin Nowak-Reppel, Steven J. Ferrara, Stefan N. Gradl, Daniel Korr, Craig A. Strathdee, Antonius ter Laak, Roman C. Hillig   +8 more
wiley   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, Volume 117, Issue 3, Page 642-652, September 2026.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

A rare case of collision tumor: Massive mucinous cystadenoma and benign mature cystic teratoma arising in the same ovary

CHRISMED Journal of Health and Research, 2017
Collision tumor means the coexistence of two adjacent, but histologically distinct tumors without histologic admixture in the same tissue and is rare incidence involving the ovary.
Reddy Ravikanth
doaj   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, Volume 293, Issue 17, Page 5340-5362, September 2026.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

High-grade transformation of papillary cystadenocarcinoma with p16 immunoreactivity arising from the base of tongue

Human Pathology: Case Reports, 2019
Papillary cystadenocarcinoma (PCC) is a rare malignant salivary gland neoplasm that accounts for less than 0.2% of primary salivary gland tumors. These tumors are characterized by the presence of invasive cystic and ductal structures and well-defined ...
Katherine Larrabee, Jena C. Patel, Terrance J. Lynn, Iman Sarami, William Quinones   +4 more
doaj   +1 more source

Papillary cystadenocarcinoma of the parotid gland: a rare sub-variant of salivary gland adenocarcinoma

Autopsy and Case Reports, 2022
Papillary cystadenocarcinoma of the salivary gland is a very rare malignant neoplasm accounting for only 2% of all salivary gland lesions. In 1991 it was first included as a separate entity in the World Health Organization (WHO) classification of ...
Satya Dutta, Biswajit Dey, Jaya Mishra, Vandana Raphael, Jonali Das, Donboklang Lynser   +5 more
doaj  

Diverse histologic appearances in pulmonary mucinous cystic neoplasia: A case report

Journal of Medical Case Reports, 2008
Introduction Primary pulmonary mucinous cystic neoplasia comprises a group of tumors, from benign cystadenoma to mucinous cystadenocarcinoma. Case presentation We report a case of primary pulmonary mucinous cystadenocarcinoma in a 75-year-old woman who ...
Wynveen Christine, Behmaram Behnaz, Haasler George, Rao Nagarjun   +3 more
doaj   +1 more source

Giant ovarian cystadenocarcinoma

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2023
Ovarian tumors represent one of the usual neoplasms of women and are responsible for almost half of the deaths from cancer of the female genital tract.
Karell Piñón-García, Yudelky Almeida-Esquivel   +1 more
doaj  

Acinar Cell Cystadenocarcinoma of the Pancreas

Case Reports in Gastroenterology, 2017
Acinar cell cystadenocarcinoma is a rare malignant epithelial neoplasm of the pancreas with a diffusely cystic, gross architecture in which the cysts are lined with neoplastic epithelial cells that demonstrate evidence of pancreatic exocrine enzyme ...
Keita Aoto, Tatsuo Shimura, Yasuhide Kofunato, Ryo Okada, Rei Yashima, Yuichiro Kiko, Seiichi Takenoshita   +6 more
doaj   +1 more source