Results 141 to 144 of about 36,977 (144)

Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine β‐synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial

Journal of Inherited Metabolic Disease, 2019
A phase 1/2 clinical trial was performed in individuals with cystathionine β synthase (CBS) deficient homocystinuria with aims to: (a) assess pharmacokinetics and safety of taurine therapy, (b) evaluate oxidative stress, inflammation, and vascular ...
J. V. Van Hove, C. Freehauf, C. Ficicioglu, Loren D. M. Pena, K. Moreau, T. Henthorn, U. Christians, Hua Jiang, T. Cowan, S. Young, M. Hite, Marisa W Friederich, S. Stabler, E. Spector, K. Kronquist, J. Thomas, P. Emmett, M. J. Harrington, L. Pyle, Geralyn Creadon‐Swindell, M. Wempe, K. Maclean   +21 more
semanticscholar   +1 more source

Deletions of the cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CSE) genes, involved in the control of hydrogen sulfide biosynthesis, significantly affect lifespan and fitness components of Drosophila melanogaster

Mechanisms of Ageing and Development, 2022
M. Shaposhnikov, A. Zakluta, N. Zemskaya, Z. Guvatova, V. Shilova, D. Yakovleva, Anastasia Gorbunova, Liubov A. Koval, N. Ulyasheva, M. Evgen'ev, O. Zatsepina, A. Moskalev   +11 more
semanticscholar   +1 more source

The role of cystathionine β-synthase in cancer.

Cellular Signalling
Yan-Wen Wang, Ti Chu, Xue-Li Wang, Yong-Qi Fan, Lei Cao, Yu-Hang Chen, Yi-Wen Zhu, Hong-Xia Liu, Xin-Ying Ji, Dong-Dong Wu   +9 more
semanticscholar   +1 more source

Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity.

Journal of Medicinal Chemistry, 2017
Brian Kawahara, T. Moller, Kayla Hu-Moore, S. Carrington, K. Faull, S. Sen, P. Mascharak   +6 more
semanticscholar   +1 more source