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Drug Discovery Today, 2013
Cysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low. Most experience with cysteamine as a drug originates from the field of the orphan disease cystinosis, in which cysteamine is prescribed to decrease intralysosomal cystine ...
Besouw, Martine +3 more
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Cysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low. Most experience with cysteamine as a drug originates from the field of the orphan disease cystinosis, in which cysteamine is prescribed to decrease intralysosomal cystine ...
Besouw, Martine +3 more
openaire +2 more sources
Adrenergic blocking action of cysteamine
Experientia, 1962Il a ete demontre que la cysteamine provoque une activation centrale adrenergique accompagnee par une liberation des catecholamines de la surrenale. Plus tard cet effet est suivi par un blocage periferique des recepteurs adrenergiques.
R, DEBIJADJI +3 more
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Nature, 1962
Evidence is given in support of the hypothesis that the radioprotective action of a group of sulfhydryl compounds such as cysteine and cysteamine is not based on the removal of oxygen but is caused by another mode of action on the cellular level. In the experiments, cysteamine in concentrations of 4 and 16 mM- bar gave dose reduction factors of 1.8 and
A J, VERGROESEN, O, VOS, L, BUDKE
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Evidence is given in support of the hypothesis that the radioprotective action of a group of sulfhydryl compounds such as cysteine and cysteamine is not based on the removal of oxygen but is caused by another mode of action on the cellular level. In the experiments, cysteamine in concentrations of 4 and 16 mM- bar gave dose reduction factors of 1.8 and
A J, VERGROESEN, O, VOS, L, BUDKE
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Effects of cysteamine on nociception in mice.
Acta pharmacologica Sinica, 2001The present study was carried to study the effects of cysteamine on nociception in mice.The pain assays were the hot plate and the tail flick test.When cysteamine, a drug well known as a somatostatin depletor, was administered 1 and 4 but not 24 h before the tests (hot plate, tail flick), the nociceptive threshold was elevated when the drug was ...
CAPASSO, Anna, A. LOIZZO
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The Journal of Pharmacology and Experimental Therapeutics, 1957
R A, SALVADOR, C, DAVISON, P K, SMITH
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R A, SALVADOR, C, DAVISON, P K, SMITH
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Challenges for cysteamine stabilization, quantification, and biological effects improvement
Journal of Pharmaceutical Analysis, 2020Hélène Greige, Catherine Charcosset
exaly
Enteric-Coated Cysteamine Bitartrate in Cystinosis Patients
Pharmaceutics, 2023, Chris Ottolenghi, Marquardt Thorsten
exaly