Results 121 to 130 of about 79,480 (272)

Integrated Analysis of HER2 Expression and ERBB2 Alterations in Bladder Cancer

open access: yesCancer Science, EarlyView.
Integrated analysis of 445 bladder cancers showed that HER2 membrane expression and ERBB2 amplification are distinct features. HER2 expression overlapped with NECTIN4 expression, whereas ERBB2 amplification was enriched in the LumU subtype and associated with poor prognosis.
Kensuke Hirosuna   +13 more
wiley   +1 more source

Ovarian pain in the mare: Clinical implications of mittelschmerz and oestrus‐related behavioural abnormalities

open access: yesEquine Veterinary Education, EarlyView.
Summary Mittelschmerz is a well‐recognised benign peri‐ovulatory pain syndrome in women and, by physiological analogy, may also occur in mares. In equine practice, peri‐ovulatory ovarian pain has been associated with transient discomfort, colic‐like signs and behavioural changes, although its true clinical relevance remains poorly defined.
G. Marino   +4 more
wiley   +1 more source

Radical cystectomy and pelvic lymphadenectomy with ileal conduit urinary diversion and abdominal wall reconstruction: an interesting case of multidisciplinary management

open access: yes, 2015
Stratos S Sofos,1 Ciaran Walsh,2 Nigel J Parr,2 Kevin Hancock11Whiston Hospital, Prescot, 2Arrowe Park Hospital, Wirral, Merseyside, UKAbstract: The ileal conduit for urinary diversion after radical cystectomy is a well-described procedure.
Walsh CJ, Sofos SS, Parr NJ, Hancock K
core  

Comparison of Costs of Radical Cystectomy vs Trimodal Therapy for Patients With Localized Muscle-Invasive Bladder Cancer.

open access: yesJAMA Surgery, 2019
Importance Earlier studies on the cost of muscle-invasive bladder cancer treatments lack granularity and are limited to 180 days. Objective To compare the 1-year costs associated with trimodal therapy vs radical cystectomy, accounting for survival and ...
S. Williams   +13 more
semanticscholar   +1 more source

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

open access: yesHistopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori   +5 more
wiley   +1 more source

The value of the hospital episode statistics to study practice and outcome of urological surgery [PDF]

open access: yes
Introduction: Despite the growing emphasis on the collection, monitoring and reporting of outcomes of surgical care within the UK, few data exist for such purposes. Equally, few data are available on disease occurrence and surgical practice in England.
Cathcart, Paul
core   +1 more source

Comparison of perioperative complications and health‐related quality of life between robot‐assisted and open radical cystectomy: A systematic review and meta‐analysis

open access: yesInternational journal of urology, 2019
To compare postoperative complications and health‐related quality of life of patients undergoing robot‐assisted radical cystectomy with those of patients undergoing open radical cystectomy.
S. Kimura   +8 more
semanticscholar   +1 more source

Hybrid grading systems improve progression risk stratification in non‐invasive papillary urothelial carcinoma and support a histomorphological continuum of disease progression

open access: yesHistopathology, EarlyView.
Hybrid grading systems significantly improve progression‐risk stratification in non‐invasive papillary urothelial carcinoma compared with the WHO 2004/2016 binary classification, with most benefit achieved by a Hybrid 3‐Tier framework. These findings support the existence of a histomorphological continuum of progression risk within the conventional ...
Jane K Nguyen   +16 more
wiley   +1 more source

LESS Radical Cystectomy

open access: yes, 2017
Laparoscopic surgery made radical cystectomy and urinary diversion a less invasive procedure but still remains one of the most complex urological techniques, prone to high rate of complications.
Cabrera Castillo, Pedro Manuel   +5 more
core   +1 more source

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