Results 111 to 120 of about 975,042 (316)

Detection of cytokines in nasal lavage samples of patients with cystic fibrosis: comparison of two different cytokine detection assays

BMC Pulmonary Medicine
Background Cystic fibrosis (CF) is a genetic multisystem disorder. Inflammatory processes, which presumably begin early in infancy, play a crucial role in the progression of the disease. The detection of inflammatory biomarkers, especially in the airways,
Teresa Fuchs, Manuela Zlamy, Thomas Zöggeler, Dorothea Appelt, Katharina Niedermayr, Anja Siedl, Verena Gasser, Johannes Eder, Helmut Ellemunter   +8 more
doaj   +1 more source

Decision letter for "PROBIOTIC USE IN ADULTS WITH CYSTIC FIBROSIS IS COMMON AND INFLUENCED BY GASTROINTESTINAL HEALTH NEEDS: A CROSS SECTIONAL SURVEY STUDY"

, 2021

openalex   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Self‐Management Interventions in Young Adults (18–30 Years) With Type 1 Diabetes, Sickle Cell Disease, and Inflammatory Bowel Disease: A Scoping Review

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Fluctuating chronic conditions (FCC) in young adults aged 18–30 years, such as type 1 diabetes (T1D), sickle cell disease (SCD), and inflammatory bowel disease (IBD), present unique self‐management challenges due to unpredictable symptom patterns that disrupt daily life.
Reham Almabadi, Lawrence Doi, Colin Chandler, Huda Alamri   +3 more
wiley   +1 more source

Real-world improvement in ultra-low-dose thoracic computed tomography scores, systemic inflammatory markers and patient-reported outcome measures after elexacaftor/tezacaftor/ivacaftor treatment

ERJ Open Research
Background Clinical trials with elexacaftor/tezacaftor/ivacaftor (ETI) in people with cystic fibrosis were associated with significant improvements in % predicted forced expiratory volume in 1 s (FEV1 % pred), sweat chloride, weight and quality of life ...
Hisham Ibrahim, Alexander T. O'Mahony, Kevin F. Deasy, Michael Waldron, Mairead McCarthy, James Dorgan, Claire Fleming, Ciara Howlett, Edel O'Riordan, Yvonne McCarthy, Sarah Twohig, Janice Mansfield, Tamara Vagg, Desmond M. Murphy, Paul O'Regan, Laura Kirwan, Joseph A. Eustace, Owen J. O'Connor, Michael M. Maher, Barry J. Plant   +19 more
doaj   +1 more source

Rubrolides A, D, P, T, U: Total Syntheses and Antibacterial Evaluation of Highly Brominated Marine Natural Products

ChemistryEurope, EarlyView.
Following the Danube Flow. The first total syntheses of highly brominated rubrolides T, U, and U‐analog, together with the efficient and divergent syntheses of rubrolides A, D, and P. The dibrominated key intermediate, obtained via a Suzuki‐Miyaura cross‐coupling reaction, is the centerpiece of the synthesis.
Jasmin Janneschütz, Paul G. Schebek, Alexander Meyer, Celina Haller, Sophia Khom, Wolfgang R. Streit, Ifey Alio, Nina Schützenmeister   +7 more
wiley   +1 more source

Efficacy of elexacaftor/tezacaftor/ivacaftor in non-cystic fibrosis bronchiectasis patients with a single pathogenic CFTR mutation: a retrospective cohort analysis

ERJ Open Research
Introduction It has previously been established that there is an increased incidence of mutations in the cystic fibrosis transmembrane regulator (CFTR) gene amongst patients with non-cystic fibrosis bronchiectasis (NCFB).
Lena Papadakis, Isabel Neuringer, Hang Lee, Anne O'Donnell, Julia Zweifach, Brenden Lawton, Leonard Sicilian, Rocio Hurtado, Tayler Stander, Lindsay Bringhurst, Christopher Richards   +10 more
doaj   +1 more source

Investigating the Ligand‐Binding Properties of N‐arylbenzimidazoles as Novel Elastase Inhibitors

ChemMedChem, EarlyView.
A series of novel N‐[(3,5‐dimethylphenyl)methyl]‐1H‐benzimidazole derivatives is designed, synthesized, and evaluated for inhibitory activity against elastase. Several compounds demonstrate an antielastase activity, including the N‐(2‐bromophenyl)‐2‐(6‐chloro‐1‐(3,5‐dimethylbenzyl)‐1H‐benzo[d]imidazol‐2‐ylthio)acetamide, showing the greatest potency ...
Giovanna Pitasi, Sonia Floris, Francesca Mancuso, Giulia Savoca, Rosaria Gitto, Antonella Fais, Laura De Luca   +6 more
wiley   +1 more source

The future of cystic fibrosis care: a global perspective.

The Lancet Respiratory Medicine, 2020
S. Bell, M. Mall, H. Gutierrez, M. Macek, S. Madge, J. Davies, P. Burgel, E. Tullis, C. Castaños, C. Castellani, C. Byrnes, F. Cathcart, S. H. Chotirmall, R. Cosgriff, I. Eichler, I. Fajac, C. Goss, P. Dřevínek, P. Farrell, A. Gravelle, T. Havermans, N. Mayer-Hamblett, N. Kashirskaya, E. Kerem, J. Mathew, E. McKone, L. Naehrlich, S. Nasr, G. Oates, C. O’Neill, Ulrike Pypops, K. Raraigh, S. Rowe, K. Southern, S. Sivam, A. Stephenson, M. Zampoli, F. Ratjen   +37 more
semanticscholar   +1 more source

Knowledge, Confidence, and Perceptions of Oral Cancer Screening Among Rural and Metropolitan Australian General Dental Practitioners: A Pilot Study

Cancer Nexus, EarlyView.
ABSTRACT Background Oral cancer is a significant public health concern, with disproportionately higher incidence and mortality in rural, regional, and remote Australia. General dental practitioners (GDPs), as frontline providers, are critical to early detection through routine screening.
Bhavika Jindal, Xia Li, Michael Stubbs, Elizabeth Fitriana Sari   +3 more
wiley   +1 more source