Results 121 to 130 of about 352,696 (330)

A Sodium Transport Inhibitory Factor in the Saliva of Patients with Cystic Fibrosis of the Pancreas [PDF]

, 1967
J. A. Mangos, Nona R. McSherry, P.J. Benke   +2 more
openalex   +1 more source

A Winogradsky-based culture system shows an association between microbial fermentation and cystic fibrosis exacerbation. [PDF]

, 2015
There is a poor understanding of how the physiology of polymicrobial communities in cystic fibrosis (CF) lungs contributes to pulmonary exacerbations and lung function decline.
Bailey, Barbara, Blake, Don, Conrad, Doug, Lim, Yan-Wei, Mienardi, Simone, Quinn, Robert A, Rohwer, Forest, Salamon, Peter, Sanchez, Savannah E, Whiteson, Katrine   +9 more
core   +1 more source

Light‐Enabled [2σ + 2π] Cycloadditions of Bicyclo[1.1.0]butanes and Alkenes by Ti‐Salen Photocatalysis

ChemistryEurope, EarlyView.
This study reports an unprecedented Ti(Salen)‐catalyzed [2σ+2π] photocycloaddition of bicyclo[1.1.0]butanes and alkenes, featuring broad substrate scope, excellent functional group tolerance, scalability, and potential pharmaceutical applications. Notably, this work represents the first application of a Ti(Salen) complex as an efficient photoredox ...
Jinping Xing, Dexia Li, Tianxiang Li, Yang Xu, Haosong Ren, Jun Zheng   +5 more
wiley   +1 more source

CFTR modulators response of S737F and T465N CFTR variants on patient-derived rectal organoids

Orphanet Journal of Rare Diseases
Background Predictions based on patient-derived materials of CFTR modulators efficacy have been performed lately in patient-derived cells, extending FDA-approved drugs for CF patients harboring rare variants.
Karina Kleinfelder, Paola Melotti, Anca Manuela Hristodor, Cristina Fevola, Giovanni Taccetti, Vito Terlizzi, Claudio Sorio   +6 more
doaj   +1 more source

Cystic fibrosis of the pancreas: structural changes in peripheral airways [PDF]

, 1968
John R. Esterly, Ella H. Oppenheimer
openalex   +1 more source

Chloride Selective, Nonprotonophoric Ion Transport with Macrocyclic Halogen Bonding Anionophores

Chemistry – A European Journal, EarlyView.
Macrocyclic halogen bonding anionophores are reported, which enable very high chloride over proton and hydroxide transport selectivity. This ion selectivity profile is key for future potential therapeutic applications, and its origin is explored through DFT and MD simulations at the membrane.
Martin Flerin, Fernanda Duarte, Matthew J. Langton   +2 more
wiley   +1 more source

Detection of cytokines in nasal lavage samples of patients with cystic fibrosis: comparison of two different cytokine detection assays

BMC Pulmonary Medicine
Background Cystic fibrosis (CF) is a genetic multisystem disorder. Inflammatory processes, which presumably begin early in infancy, play a crucial role in the progression of the disease. The detection of inflammatory biomarkers, especially in the airways,
Teresa Fuchs, Manuela Zlamy, Thomas Zöggeler, Dorothea Appelt, Katharina Niedermayr, Anja Siedl, Verena Gasser, Johannes Eder, Helmut Ellemunter   +8 more
doaj   +1 more source

Abridging the 22‐Item Sino‐Nasal Outcome Test (SNOT‐22) in People With Cystic Fibrosis: Limiting Survey Burden

International Forum of Allergy &Rhinology, EarlyView.
Haidee Chen, Jakob L. Fischer, Tristan D. Tibbe, Ahmad R. Sedaghat, Ethan J. Han, Jess C. Mace, Jeremiah A. Alt, Todd E. Bodner, Naweed I. Chowdhury, Yuqing A. Gao, Peter H. Hwang, Ashoke Khanwalkar, Adam J. Kimple, Jivianne T. Lee, Douglas A. Li, Meghan Norris, Jayakar V. Nayak, Cameran Collins, Zara M. Patel, Katie Phillips, Katie Poch, Rodney J. Schlosser, Kristine A. Smith, Zachary M. Soler, Jeffrey D. Suh, Grant A. Turner, Marilene B. Wang, Anne Getz, Ashleigh Halderman, Sei Chung, Jeremy P. Tervo, Jonathan B. Overdevest, Ryan A. Cotter, Milene T. Saavedra, Jennifer L. Taylor‐Cousar, Myung‐Shin Sim, Daniel M. Beswick   +36 more
wiley   +1 more source

Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma

ChemMedChem, Accepted Article.
Glioblastoma (GBM) is the most common and aggressive malignant grade IV brain tumour and is one of the most difficult types of brain cancer to treat with a high incidence of resistance to traditionally used chemotherapeutics. Pyrazolopyrimidinones are fused nitrogen‐containing heterocyclic systems which are a scaffold in several bioactive drugs and ...
Kate Byrne, Natalia Bednarz, Ciara McEvoy, John C. Stephens, James F. Curtin, Gemma Kinsella   +5 more
wiley   +1 more source

Considerations in Transition of Pediatric Neurology Patients to Adult Care

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Transition refers to the planned, coordinated movement of adolescents from the child‐ and family‐centered environment of pediatric care to the adult healthcare system. A well‐structured transition process is essential for ensuring adolescents with chronic health conditions continue to thrive in young adulthood.
Asif Doja, Katherine Muir, Megan E. Harrison, Sarah Healy, Ashley Vandermorris, Alene Toulany   +5 more
wiley   +1 more source