Results 121 to 130 of about 1,046,440 (397)
Comparing Online Community Structure of Patients of Chronic Diseases [PDF]
In this paper we compare the social network structure of people talking about Crohn's disease, Cystic Fibrosis, and Type 1 diabetes on Facebook and Twitter. We find that the Crohn's community's contributors are most emotional on Facebook and Twitter and most negative on Twitter, while the T1D community's communication network structure is most cohesive.
arxiv
Early diagnosis and intervention in cystic fibrosis: Imagining the unimaginable [PDF]
Cystic fibrosis is the most common life-shortening genetic disease affecting Caucasians, clinically manifested by fat malabsorption, poor growth and nutrition, and recurrent sinopulmonary infections. Newborn screening programs for cystic fibrosis are now
Coverstone, Andrea M, Ferkol, Thomas W
core +1 more source
ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson+10 more
wiley +1 more source
Claim Detection in Biomedical Twitter Posts [PDF]
Social media contains unfiltered and unique information, which is potentially of great value, but, in the case of misinformation, can also do great harm. With regards to biomedical topics, false information can be particularly dangerous. Methods of automatic fact-checking and fake news detection address this problem, but have not been applied to the ...
arxiv
A retrospective analysis of longitudinal changes in bone mineral content in cystic fibrosis [PDF]
Background: We aimed to describe the longitudinal changes in bone mineral content and influencing factors, in children with cystic fibrosis (CF). Methods: One hundred children (50 females) had dual X-ray absorptiometry (DXA) performed.
Ahmed, Syed Faisal+7 more
core +1 more source
Boosting Joint Models for Longitudinal and Time-to-Event Data [PDF]
Joint Models for longitudinal and time-to-event data have gained a lot of attention in the last few years as they are a helpful technique to approach common a data structure in clinical studies where longitudinal outcomes are recorded alongside event times.
arxiv
Bayesian Quantile-Based Joint Modelling of Repeated Measurement and Time-to-Event data, with an Application to Lung Function Decline and Time to Infection in Patients with Cystic Fibrosis [PDF]
Background: The most widely used approach to joint modelling of repeated measurement and time to event data is to combine a linear Gaussian random effects model for the repeated measurements with a log-Gaussian frailty model for the time-to-event outcome, linking the two through some form of correlation structure between the random effects and the log ...
arxiv
MRSA eradication of newly acquired lower respiratory tract infection in cystic fibrosis [PDF]
UK cystic fibrosis (CF) guidelines recommend eradication of methicillin-resistant Staphylococcus aureus (MRSA) when cultured from respiratory samples.
Downey, DG+7 more
core +3 more sources
Tezacaftor–Ivacaftor in Residual‐Function Heterozygotes with Cystic Fibrosis
BACKGROUND Cystic fibrosis is an autosomal recessive disease caused by mutations in the CFTR gene that lead to progressive respiratory decline. Some mutant CFTR proteins show residual function and respond to the CFTR potentiator ivacaftor in vitro ...
S. Rowe+12 more
semanticscholar +1 more source
ABSTRACT Background Type 2 inflammation dominates eosinophilic chronic rhinosinusitis (eCRS) and adult onset asthma. IL‐4, ‐5, and ‐13 are prominent disease mediators. Disease control can be achieved with biologic therapies. However, despite some patients entering remission, others experience poor control. Aim We aimed to describe eCRS patients treated
Peta‐Lee Sacks+8 more
wiley +1 more source