Results 121 to 130 of about 1,132,527 (387)
Advanced Science, EarlyView.Using a dynamic, tri‐culture air‐blood barrier model, this study reveals that macrophage‐mediated transport governs micron‐sized particle translocation under cyclic strain. The process is highly size‐dependent that 2 µm particles are transported by macrophages, 0.2 µm particles diffuse passively, and 5 µm particles are effectively blocked.
Yongjian Li +3 more
wiley +1 more source
Near‐Infrared Triggered Anion Transport Induces Cancer Cell Death
Angewandte Chemie, EarlyView.Photo‐responsive transmembrane anion transporters that are activated with NIR light are reported. Experiments in cancer cells revealed that NIR activation of the ionophore triggered near‐IR light‐dependent chloride influx and triggered cell death. Abstract Artificial transmembrane anion carriers have shown potential in biological research and medicine,
Manzoor Ahmad +3 more
wiley +2 more sources
Worldwide rates of diagnosis and effective treatment for cystic fibrosis.
Journal of Cystic Fibrosis, 2022 Jonathan Guo, A. Garratt, A. Hill
semanticscholar +1 more source
Advanced Science, EarlyView.The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang +12 more
wiley +1 more source
Transmembrane Transport of cAMP and AMP Using a Two Component Small Molecule Transport System
Angewandte Chemie, EarlyView.Transmembrane transport of the nucleotides cAMP (cyclic adenosine monophosphate) and AMP (adenosine monophosphate) is challenging, but can be achieved using a two‐component system consisting of a synthetic anionophore (e.g., squaramides) and a lipophilic thymine derivative.
Uththara M.C. Rathnaweera +7 more
wiley +2 more sources
Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment
Advanced Science, EarlyView.Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr. +20 more
wiley +1 more source
Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor
Nature Communications, 2017 Asthma is characterized by abnormal airway hyperresponsiveness. Here the authors identify BPIFA1 as a factor secreted by airway epithelial cells, and show that it regulates contractility of airway smooth muscle cells by binding to and regulating the ...
Tongde Wu +10 more
doaj +1 more source
Early respiratory viral infections in infants with cystic fibrosis [PDF]
, 2015 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
A Peshkin +41 more
core +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Cystic fibrosis (CF) monitoring relies on computed tomography (CT), but ultra‐short echo time MRI (UTE‐MRI) offers a radiation‐free alternative. However, its clinical adoption is hindered by the laborious and subjective manual analysis, which prevents standardized quantification of bronchial abnormalities.
Fabien Baldacci +3 more
openalex +2 more sources
Screw‐Based Pill for Intelligent Robotic Extraction of Viscous Fluids in Medical Applications
Advanced Intelligent Systems, EarlyView.Screw‐based pill for intelligent robotic extraction (S‐PIRE) is a magnetically actuated smart capsule with a motorized screw, 3‐axis sensor, and Bluetooth control for site‐specific and minimally invasive remote sampling of viscous fluids, overcoming passive diffusion limitations.
Prima Dewi Sinawang +6 more
wiley +1 more source