Results 261 to 270 of about 352,696 (330)

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

Aging Cell, EarlyView.
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar, Mark A. Watson, Bikem Soygur, Fei Wu, Joanna Bons, Hannah Anvari, Tomiris Atazhanova, Nicolas Martin, Tommy Tran, Kevin Schneider, Jacob P. Rose, Daniel Winer, Elisheva Shanes, Mary Ellen G. Pavone, Judith Campisi, David Furman, Simon Melov, Birgit Schilling, Francesca E. Duncan   +18 more
wiley   +1 more source

The effect of elexacaftor-tezacaftor-ivacaftor on liver stiffness in children with cystic fibrosis. [PDF]

J Pediatr Gastroenterol Nutr
Diemer S, Elidottir H, Eklund EA, Påhlman LI, Hansen C.   +4 more
europepmc   +1 more source

Systematic Multi‐Trait Study of Genetic Correlation and Causality Relationships Between General Medical Conditions and Mental Disorders

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Increasing evidence has highlighted bidirectional associations between mental disorders and general medical conditions, with underlying causes ranging from lifestyle habits and side effects from medications to genetic contributions. Novel methods now provide a way to estimate the shared genetic underpinnings and the possibility of
Ron Nudel, Maria Da Re, Michael E. Benros   +2 more
wiley   +1 more source

Evaluation of Cystic Fibrosis Newborn Screening and Follow-Up Process in Georgia (2022-2023). [PDF]

Int J Neonatal Screen
Vardosanidze N, Kavlashvili N, Margvelashvili L, Kvlividze O, Diakonidze M, Iordanishvili S, Agladze D.   +6 more
europepmc   +1 more source

Examining the role of freebase nicotine in the harm reduction potential of oral nicotine pouches versus moist snuff: A randomized crossover trial

Addiction, EarlyView.
Abstract Background and aims Oral nicotine pouches (ONPs) contain varying proportions of freebase nicotine (FBN), with higher FBN expected to increase nicotine delivery across the oral mucosa. Because ONPs contain fewer toxicants than moist snuff and may serve as a reduced harm alternative for smokeless tobacco, we compared how the FBN in ONPs affects ...
Brittney Keller‐Hamilton, Hayley Curran, Leanne Atkinson, Sriya Suraapaneni, Alice Hinton, Kirsten Chrzan, Darren Mays, Ahmad El‐Hellani, Clark W. Wilson, Marielle C. Brinkman, Theodore L. Wagener   +10 more
wiley   +1 more source

Impact of body mass index on outcomes of non-cystic fibrosis bronchiectasis. [PDF]

BMJ Open Respir Res
Hsu WH, Shiau BW, Wei YF, Lai CC, Chen CY.   +4 more
europepmc   +1 more source

Clinical Characteristics of Difficult‐To‐Treat Allergic Bronchopulmonary Aspergillosis and Its Prediction Score

Allergy, EarlyView.
A retrospective cohort of newly diagnosed treatment‐naive patients with ABPA in Japan who were followed up for up to 3 years after the primary diagnosis was analyzed to explore the clinical remission rate and clinical characteristics of ABPA resistant to standard treatment or prone to exacerbation during/after treatment.
Jun Tanaka, Tsuyoshi Oguma, Takashi Ishiguro, Hirokazu Taniguchi, Teruaki Nishiuma, Hiroki Tateno, Hisako Matsumoto, Naoki Koshimizu, Yutaka Ito, Kazuto Matsunaga, Hidekazu Matsushima, Yoshitaka Uchida, Koshi Yokomura, Hirotaka Yasuba, Junko Suzuki, Shigeaki Hattori, Naoki Okada, Katsuyoshi Tomomatsu, Koichiro Asano, on behalf of ABPM Research Program   +19 more
wiley   +1 more source

Clinical Disorders in Cystic Fibrosis That Affect Emergency Procedures-A Case Report and Review. [PDF]

J Clin Med
Jarzynka S, Dobrosz M, Jaworski S, Jóźwicki K, Wierzba S, Barbarska O, Minkiewicz-Zochniak A.   +6 more
europepmc   +1 more source

Impact of Elexacaftor/Tezacaftor/Ivacaftor on Fecal Elastase-1 in Children With Cystic Fibrosis. [PDF]

Pediatr Pulmonol
Sankararaman S, Prunty L, Pamer C, Thavamani A, Roesch E, Schindler T.   +5 more
europepmc   +1 more source

Low testosterone in primary infertile men is associated with a history of maternal obesity during pregnancy: Findings from a cross‐sectional study

Andrology, EarlyView.
Abstract Background Maternal obesity increases offspring obesity risk, but limited data exist on its association with reproductive hormones in infertile males. Objectives To investigate the impact of maternal obesity during pregnancy on total testosterone levels in primary infertile men.
Fausto Negri, Luca Boeri, Edoardo Pozzi, Massimiliano Raffo, Riccardo Ramadani, Gabriele Birolini, Federica Passarelli, Christian Corsini, Federico Belladelli, Alessandro Bertini, Rayan Matloob, Alessia d'Arma, Michael L. Eisenberg, Francesco Montorsi, Andrea Salonia   +14 more
wiley   +1 more source