Results 261 to 270 of about 1,122,604 (303)
Some of the next articles are maybe not open access.
Primary Care: Clinics in Office Practice, 1977
Cystic fibrosis has been regarded as a disease of infants. Yet, with improved management, a high percentage of patients how survive into young adulthood. In addition, mild cases may not be detected until long after infance. The older patient often has minimal symptoms, and the majority are socially active and productive.
openaire +2 more sources
Cystic fibrosis has been regarded as a disease of infants. Yet, with improved management, a high percentage of patients how survive into young adulthood. In addition, mild cases may not be detected until long after infance. The older patient often has minimal symptoms, and the majority are socially active and productive.
openaire +2 more sources
Is it cystic fibrosis? The challenges of diagnosing cystic fibrosis
Paediatric Respiratory Reviews, 2019The spectrum of conditions caused by abnormal CFTR function is broad - from 'classic' cystic fibrosis (CF) to single organ conditions termed CFTR-related disorders. Defining and securing the diagnosis in an important minority of patients can be a challenge as the sweat test is equivocal or normal; the impact this has on the patient (at different stages
openaire +3 more sources
Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.
Science, 1989J. Riordan +10 more
semanticscholar +2 more sources
Nature Reviews Disease Primers
Cystic fibrosis is a rare genetic disease caused by mutations in CFTR, the gene encoding cystic fibrosis transmembrane conductance regulator (CFTR). The discovery of CFTR in 1989 has enabled the unravelling of disease mechanisms and, more recently, the development of CFTR-directed therapeutics that target the underlying molecular defect.
Marcus A. Mall +5 more
openaire +2 more sources
Cystic fibrosis is a rare genetic disease caused by mutations in CFTR, the gene encoding cystic fibrosis transmembrane conductance regulator (CFTR). The discovery of CFTR in 1989 has enabled the unravelling of disease mechanisms and, more recently, the development of CFTR-directed therapeutics that target the underlying molecular defect.
Marcus A. Mall +5 more
openaire +2 more sources
Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR
Yearbook of Pulmonary Disease, 2016S. Willsie
semanticscholar +1 more source
Molecular and cellular mechanisms of liver fibrosis and its regression
Nature Reviews Gastroenterology and Hepatology, 2020Tatiana Kisseleva
exaly
Hepatic inflammatory responses in liver fibrosis
Nature Reviews Gastroenterology and Hepatology, 2023Linda Hammerich, Frank Tacke
exaly