Results 31 to 40 of about 925,943 (256)

G-formula for causal inference via multiple imputation [PDF]

open access: yesarXiv, 2023
G-formula is a popular approach for estimating treatment or exposure effects from longitudinal data that are subject to time-varying confounding. G-formula estimation is typically performed by Monte-Carlo simulation, with non-parametric bootstrapping used for inference.
arxiv  

Six minute walk test in Italian children with cystic fibrosis aged 6 and 11

open access: yesMonaldi Archives for Chest Disease, 2021
Six Minute Walk Test (6MWT) is a field exercise test widely used in clinical practice, both in adults and in pediatric patients. The primary aim of the study is to evaluate the physical performance of the subjects and compare them with the predicted ...
Diletta Innocenti   +11 more
doaj   +1 more source

Quantification of Lung Abnormalities in Cystic Fibrosis using Deep Networks [PDF]

open access: yesProc. SPIE 10574, Medical Imaging 2018: Image Processing, 105741G (2 March 2018), 2018
Cystic fibrosis is a genetic disease which may appear in early life with structural abnormalities in lung tissues. We propose to detect these abnormalities using a texture classification approach. Our method is a cascade of two convolutional neural networks. The first network detects the presence of abnormal tissues.
arxiv   +1 more source

Can early Burkholderia cepacia complex infection in cystic fibrosis be eradicated with antibiotic therapy?

open access: yesFrontiers in Cellular and Infection Microbiology, 2011
IntroductionOrganisms of the Burkholderia cepacia complex (BCC) are important pathogens in cystic fibrosis (CF). The majority of those who acquire BCC develop chronic infection but it can also result in rapid decline in a significant minority.
Alex eHorsley   +7 more
doaj   +1 more source

Diagnostic agreement among experts assessing adults presenting with possible cystic fibrosis: need for improvement and implications for patient care

open access: yesERJ Open Research, 2022
Background Increasing awareness of milder presentations of cystic fibrosis (CF) and greater interest in non-CF bronchiectasis are likely to lead to more CF screening by respiratory clinicians. As a result, adults who may not strictly fulfil CF diagnostic
Alessandro N. Franciosi   +8 more
doaj   +1 more source

VX‐445–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles

open access: yesNew England Journal of Medicine, 2018
BACKGROUND VX‐445 is a next‐generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore Phe508del CFTR protein function in patients with cystic fibrosis when administered with tezacaftor and ivacaftor (VX‐445 ...
D. Keating   +19 more
semanticscholar   +1 more source

Does cystic fibrosis constitute an advantage in COVID-19 infection?

open access: yesItalian Journal of Pediatrics, 2020
The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may constitute a risk factor in COVID-19. Moreover, respiratory viruses were generally associated with
Valentino Bezzerri   +3 more
doaj   +1 more source

Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface

open access: yesClinical Microbiology Reviews, 2019
In human pathophysiology, the clash between microbial infection and host immunity contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this phenomenon, wherein a dysfunctional, hyperinflammatory immune response combined with ...
Sankalp Malhotra, D. Hayes, D. Wozniak
semanticscholar   +1 more source

How are the ancient cystic fibrosis patients? Cystic fibrosis diagnosed over 60 years-old

open access: yesRespiratory Medicine Case Reports, 2017
Background and aims: To specify the prevalence of patients diagnosed with CF at age of ≥60 year-old and to analyze their characteristics. Patients and methods: Observational study of CF patients which were diagnosed at age ≥60 year-old.
C. Prados   +10 more
doaj   +1 more source

Understanding Biofilm-Phage Interactions in Cystic Fibrosis Patients Using Mathematical Frameworks [PDF]

open access: yesarXiv, 2023
When planktonic bacteria adhere together to a surface, they begin to form biofilms, or communities of bacteria. Biofilm formation in a host can be extremely problematic if left untreated, especially since antibiotics can be ineffective in treating the bacteria.
arxiv  

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