Results 31 to 40 of about 352,696 (330)

Lack of Correlation Between Pulmonary Disease and Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Cystic Fibrosis: A Case Report [PDF]

, 2013
Introduction: Mutations in both alleles of the cystic fibrosis transmembrane conductance regulator gene result in the disease cystic fibrosis, which usually manifests as chronic sinopulmonary disease, pancreatic insufficiency, elevated sodium chloride ...
Asher, Daniel, Cannon, Carolynn L, Cleveland, Robert Harris, Colin, Andrew A, García, Christopher, Knowles, Michael R, Levy, Hara, Pier, Gerald B.   +7 more
core   +1 more source

An exploratory study investigating factors associated with adherence to chest physiotherapy and exercise in adults with cystic fibrosis [PDF]

, 2009
Copyright @ 2009 European Cystic Fibrosis Society. This article is available through Elsevier's Open Access Archives and covered by Elsevier's user license: http://www.elsevier.com/about/open-access/open-access-policies/oa-license-policy/elsevier-user ...
Abbott, Cockburn, Conway, Dodge, Lynn B. Myers, Myers, Myers, Myers, Sawicki, White   +9 more
core   +1 more source

Does cystic fibrosis constitute an advantage in COVID-19 infection?

Italian Journal of Pediatrics, 2020
The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may constitute a risk factor in COVID-19. Moreover, respiratory viruses were generally associated with
Valentino Bezzerri, Francesca Lucca, Sonia Volpi, Marco Cipolli   +3 more
doaj   +1 more source

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

Nature Communications, 2021
Premature termination codons can cause early translation termination and lead to disease. Here the authors perform a screen to identify compounds with readthrough activity and show that these reduce eRF1 levels to suppress premature termination ...
Jyoti Sharma, Ming Du, Eric Wong, Venkateshwar Mutyam, Yao Li, Jianguo Chen, Jamie Wangen, Kari Thrasher, Lianwu Fu, Ning Peng, Liping Tang, Kaimao Liu, Bini Mathew, Robert J. Bostwick, Corinne E. Augelli-Szafran, Hermann Bihler, Feng Liang, Jerome Mahiou, Josef Saltz, Andras Rab, Jeong Hong, Eric J. Sorscher, Eric M. Mendenhall, Candice J. Coppola, Kim M. Keeling, Rachel Green, Martin Mense, Mark J. Suto, Steven M. Rowe, David M. Bedwell   +29 more
doaj   +1 more source

TAS2R38 is a novel modifer gene in patients with cystic fbrosis [PDF]

, 2020
The clinical manifestation of cystic fbrosis (CF) is heterogeneous also in patients with the same cystic fbrosis transmembrane regulator (CFTR) genotype and in afected sibling pairs.
Amato, F., Carnovale, V, Castaldo, A, Cernera, G, Cimbalo, C, Comegna, M, DI LULLO, ANTONELLA MIRIAM, Gelzo, M, Iacotucci, P, Raia, V, Tosco, A   +10 more
core   +1 more source

Can early Burkholderia cepacia complex infection in cystic fibrosis be eradicated with antibiotic therapy?

Frontiers in Cellular and Infection Microbiology, 2011
IntroductionOrganisms of the Burkholderia cepacia complex (BCC) are important pathogens in cystic fibrosis (CF). The majority of those who acquire BCC develop chronic infection but it can also result in rapid decline in a significant minority.
Alex eHorsley, Alex eHorsley, Kevin eWebb, Kevin eWebb, Rowland eBright-Thomas, John eGovan, Andrew M Jones, Andrew M Jones   +7 more
doaj   +1 more source

Six minute walk test in Italian children with cystic fibrosis aged 6 and 11

Monaldi Archives for Chest Disease, 2021
Six Minute Walk Test (6MWT) is a field exercise test widely used in clinical practice, both in adults and in pediatric patients. The primary aim of the study is to evaluate the physical performance of the subjects and compare them with the predicted ...
Diletta Innocenti, Eleonora Masi, Giovanni Taccetti, Marco Genito, Elena Balestri, Anna Rita Berghelli, Maria Antonietta Ciciretti, Francesca Collini, Patrizia Fanzaghi, Annalisa Fogazzi, Paola Leone, Riccardo Guarise   +11 more
doaj   +1 more source

Relationship between pulmonary exacerbations and daily physical activity in adults with cystic fibrosis [PDF]

, 2015
The aim of this study was to examine the relationship between pulmonary exacerbations and physical activity (PA) in adults with cystic fibrosis (CF)
Banya, Winston, Bilton, Diana, DI PAOLO, Marcello, Hopkinson, Nicholas S, Palange, Paolo, Quattrucci, Serena, Savi, Daniela, Simmonds, Nicholas   +7 more
core   +2 more sources

Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]

, 2010
Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core   +2 more sources

Diagnostic agreement among experts assessing adults presenting with possible cystic fibrosis: need for improvement and implications for patient care

ERJ Open Research, 2022
Background Increasing awareness of milder presentations of cystic fibrosis (CF) and greater interest in non-CF bronchiectasis are likely to lead to more CF screening by respiratory clinicians. As a result, adults who may not strictly fulfil CF diagnostic
Alessandro N. Franciosi, April Tanzler, Jodi Goodwin, Pearce G. Wilcox, George M. Solomon, Albert Faro, Noel G. McElvaney, Damian G. Downey, Bradley S. Quon   +8 more
doaj   +1 more source