Results 291 to 300 of about 1,427,030 (364)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

open access: yesAdvanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko   +16 more
wiley   +1 more source

Primary Psoas Muscle Multiple Hydatid Cysts, Presenting as a Psoas Abscess: A Rare Case Report. [PDF]

open access: yesInt Med Case Rep J
Nazari FA   +5 more
europepmc   +1 more source

Mistletoe‐ and Mussel‐Inspired Fabrication of Hierarchically Structured Protein‐Cellulose Scaffolds From Biomolecular Condensates

open access: yesAdvanced Materials, EarlyView.
Merging materials processing tricks inspired by mussel and mistletoe fiber fabrication, solutions of cationic mussel byssus proteins were mixed with modified anionic nanocrystalline cellulose, producing distinctive core‐shell condensates. Simple processing of condensate suspensions using freeze‐drying produced hierarchically structured porous protein ...
Hamideh R. Alanagh   +9 more
wiley   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton   +2 more
wiley   +1 more source

Membrane Semi‐Permeability and Ion Selectivity in Chemiosmosis: Open Systems Volume Dependence of Electrolyte Chemistry

open access: yesAdvanced Materials Interfaces, EarlyView.
Very small cellular compartments can break electroneutrality and harness proton gradients without active transport structures, whereas larger volumes cannot, underscoring why life's critical energy processes are confined in microscopic spaces. ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid ...
Josep M. Ribó   +4 more
wiley   +1 more source

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